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package com.hfg.bio.seq.pattern;

import java.util.ArrayList;
import java.util.List;
import java.util.regex.Matcher;

import com.hfg.bio.seq.BioSequenceType;
import com.hfg.bio.seq.Protein;
import com.hfg.bio.seq.SeqLocation;

//------------------------------------------------------------------------------
/**
 Container for a protein pattern (motif).
 

From the PROSITE user manual:

The patterns are described using the following conventions:

  • The standard IUPAC one-letter codes for the amino acids are used.
  • The symbol 'x' is used for a position where any amino acid is accepted.
  • Ambiguities are indicated by listing the acceptable amino acids for a given position, between square parentheses '[ ]'. For example: [ALT] stands for Ala or Leu or Thr.
  • Ambiguities are also indicated by listing between a pair of curly brackets '{ }' the amino acids that are not accepted at a given position. For example: {AM} stands for any amino acid except Ala and Met.
  • Each element in a pattern is separated from its neighbor by a '-'.
  • Repetition of an element of the pattern can be indicated by following that element with a numerical value or a numerical range between parenthesis. Examples: x(3) corresponds to x-x-x, x(2,4) corresponds to x-x or x-x-x or x-x-x-x.
  • When a pattern is restricted to either the N- or C-terminal of a sequence, that pattern either starts with a '<' symbol or respectively ends with a '>' symbol. In some rare cases (e.g. PS00267 or PS00539), '>' can also occur inside square brackets for the C-terminal element. 'F-[GSTV]-P-R-L-[G>]' means that either 'F-[GSTV]-P-R-L-G' or 'F-[GSTV]-P-R-L>' are considered.
  • A period ends the pattern.
Examples:
    PA   [AC]-x-V-x(4)-{ED}.
   
This pattern is translated as: [Ala or Cys]-any-Val-any-any-any-any-{any but Glu or Asp}
    PA   <A-x-[ST](2)-x(0,1)-V.
   
This pattern, which must be in the N-terminal of the sequence ('<'), is translated as: Ala-any-[Ser or Thr]-[Ser or Thr]-(any or none)-Val
@author J. Alex Taylor, hairyfatguy.com */ //------------------------------------------------------------------------------ // com.hfg Library // // This library is free software; you can redistribute it and/or // modify it under the terms of the GNU Lesser General Public // License as published by the Free Software Foundation; either // version 2.1 of the License, or (at your option) any later version. // // This library is distributed in the hope that it will be useful, // but WITHOUT ANY WARRANTY; without even the implied warranty of // MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU // Lesser General Public License for more details. // // You should have received a copy of the GNU Lesser General Public // License along with this library; if not, write to the Free Software // Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA // // J. Alex Taylor, President, Founder, CEO, COO, CFO, OOPS hairyfatguy.com // [email protected] //------------------------------------------------------------------------------ public class ProteinPattern extends SeqPattern { //########################################################################### // CONSTRUCTORS //########################################################################### //-------------------------------------------------------------------------- public ProteinPattern(String inPrositePattern) { super(inPrositePattern); } //########################################################################### // PUBLIC METHODS //########################################################################### //-------------------------------------------------------------------------- public BioSequenceType getBioSequenceType() { return BioSequenceType.PROTEIN; } //-------------------------------------------------------------------------- public ProteinPattern setIgnoreGaps(boolean inValue) { return (ProteinPattern) super.setIgnoreGaps(inValue); } //-------------------------------------------------------------------------- @Override public ProteinPattern setMaxMismatches(int inValue) { return (ProteinPattern) super.setMaxMismatches(inValue); } //-------------------------------------------------------------------------- protected ProteinPatternMatch createMatch(String inSeq, SeqLocation inLocation) { return new ProteinPatternMatch(this, inSeq, inLocation); } }




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