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/*
* The MIT License
*
* Copyright (c) 2014 The Broad Institute
*
* Permission is hereby granted, free of charge, to any person obtaining a copy
* of this software and associated documentation files (the "Software"), to deal
* in the Software without restriction, including without limitation the rights
* to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
* copies of the Software, and to permit persons to whom the Software is
* furnished to do so, subject to the following conditions:
*
* The above copyright notice and this permission notice shall be included in
* all copies or substantial portions of the Software.
*
* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
* IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
* FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
* AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
* LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
* OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
* THE SOFTWARE.
*/
package picard.fingerprint;
/**
* Represents a set of HaplotypeProbabilities that were derived from a single SNP
* genotype at a point in time.
*/
public class HaplotypeProbabilitiesFromGenotype extends HaplotypeProbabilities {
private final Snp snp;
private final double[] likelihoods;
@Override
public HaplotypeProbabilitiesFromGenotype deepCopy() {
return new HaplotypeProbabilitiesFromGenotype(this);
}
@SuppressWarnings("CopyConstructorMissesField")
public HaplotypeProbabilitiesFromGenotype(final HaplotypeProbabilitiesFromGenotype other) {
this(other.snp, other.getHaplotype(), other.likelihoods[0], other.likelihoods[1], other.likelihoods[2]);
}
public HaplotypeProbabilitiesFromGenotype(final Snp snp, final HaplotypeBlock haplotypeBlock,
final double AA, final double Aa, final double aa) {
super(haplotypeBlock);
this.snp = snp;
this.likelihoods = new double[] {AA, Aa, aa};
}
/** Returns the SNP who's genotype was used to construct the likelihoods. */
@Override public Snp getRepresentativeSnp() { return snp; }
// simply returns the _likelihoods_ that were passed into the constructor.
public double[] getLikelihoods() {
return likelihoods;
}
@Override
public HaplotypeProbabilitiesFromGenotype merge(final HaplotypeProbabilities other) {
if (!this.getHaplotype().equals(other.getHaplotype())) {
throw new IllegalArgumentException("Mismatched haplotypes in call to HaplotypeProbabilities.merge(): " +
getHaplotype() + ", " + other.getHaplotype());
}
if (!(other instanceof HaplotypeProbabilitiesFromGenotype)) {
throw new IllegalArgumentException("Can only merge HaplotypeProbabilities of same class.");
}
for (Genotype g : Genotype.values()) {
this.likelihoods[g.v] = this.likelihoods[g.v] * other.getLikelihoods()[g.v];
}
return this;
}
}
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