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/**
 * Licensed to the Apache Software Foundation (ASF) under one
 * or more contributor license agreements.  See the NOTICE file
 * distributed with this work for additional information
 * regarding copyright ownership.  The ASF licenses this file
 * to you under the Apache License, Version 2.0 (the
 * "License"); you may not use this file except in compliance
 * with the License.  You may obtain a copy of the License at
 *
 *   http://www.apache.org/licenses/LICENSE-2.0
 *
 * Unless required by applicable law or agreed to in writing,
 * software distributed under the License is distributed on an
 * "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
 * KIND, either express or implied.  See the License for the
 * specific language governing permissions and limitations
 * under the License.
 */

/* -------------------------------- Package --------------------------------- */

package com.github.jessemull.microflexbiginteger.stat;

/* ----------------------------- Dependencies ------------------------------- */

import java.math.BigDecimal;
import java.util.ArrayList;
import java.util.Collection;
import java.util.List;
import java.util.Map;
import java.util.TreeMap;

import com.google.common.base.Preconditions;

import com.github.jessemull.microflexbiginteger.plate.Plate;
import com.github.jessemull.microflexbiginteger.plate.Well;
import com.github.jessemull.microflexbiginteger.plate.WellSet;

/**
 * This class performs weighted statistical operations for BigInteger plate stacks, 
 * plates, wells and well sets. To create a custom weighted statistical operation 
 * extend this class and override the calculate methods using the appropriate 
 * weighted statistical operation. 
 * 
 * 

* * From wikipedia: a weight function is a mathematical device used when performing * a sum, integral, or average to give some elements more "weight" or influence on * the result than other elements in the same set. In statistics a weighted function * is often used to correct bias. The weighted statistic class implements a weighted * function by accepting an array of values as weights. The values in each well of * the stack, plate, set or well are multiplied by the values within the double * array prior to the statistical calculation. * *

* * Weighted statistical operations can be performed on stacks, plates, sets and * wells using standard or aggregated functions. Standard functions calculate the * desired statistic for each well in the stack, plate or set. Aggregated functions * aggregate the values from all the wells in the stack, plate or set and perform * the weighted statistical operation on the aggregated values. Both standard and * aggregated functions can be performed on a subset of data within the stack, * plate, set or well. * *

* * The methods within the MicroFlex library are meant to be flexible and the * descriptive statistic object supports operations using a single stack, plate, * set or well as well as collections and arrays of stacks, plates, sets or wells. * * * * * * * * * * * * * * * * * * *
Operation
Beginning
Index
Length of
Subset
Input/Output
* * * * *
Standard
*
* * * * *
+/-
*
* * * * *
+/-
*
* * * * * * * *
Accepts a single well, set, plate or stack and an array of weights as input
Multiplies the values in each well of a well, set, plate or stack by the values *
in the weights array then calculates the statistic using the weighted values
*
* * * * *
Aggregated
*
* * * * *
+/-
*
* * * * *
+/-
*
* * * * * * * *
Accepts a single well/set/plate/stack or a collection/array of wells/sets/plates/stacks *
and an array of weights as input
Multiplies the values in each well of a well, set, plate or stack by the values in the *
weights array, aggregates the data from all the wells in the well/set/plate/stack then *
calculates the statistic using the aggregated weighted values
*
* * @author Jesse L. Mull * @update Updated Oct 18, 2016 * @address http://www.jessemull.com * @email [email protected] */ public abstract class DescriptiveStatisticWeights extends DescriptiveStatistic { /* ---------------- Well statistics for all plate wells ----------------- */ /** * Returns the weighted statistic for each plate well. * @param Plate the plate * @param double[] weights for the data set * @return map of wells and results */ public Map plate(Plate plate, double[] weights) { Preconditions.checkNotNull(plate, "The plate value cannot be null."); Map result = new TreeMap(); for (Well well : plate) { Well clone = new Well(well); result.put(clone, well(well, weights)); } return result; } /** * Returns the weighted statistic for each plate well using the values between the * beginning and ending indices. * @param Plate the plate * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return map of wells and results */ public Map plate(Plate plate, double[] weights, int begin, int length) { Preconditions.checkNotNull(plate, "The plate value cannot be null."); Map result = new TreeMap(); for (Well well : plate) { Well clone = new Well(well); result.put(clone, well(well, weights, begin, length)); } return result; } /* --------------------- Aggregated plate statistics ------------------- */ /** * Returns the aggregated weighted statistic for the plate. * @param Plate the plate * @param double[] weights for the data set * @return the aggregated result */ public BigDecimal platesAggregated(Plate plate, double[] weights) { Preconditions.checkNotNull(plate, "The plate cannot be null."); Preconditions.checkNotNull(weights, "Weights array cannot be null."); List aggregated = new ArrayList(); for (Well well : plate) { List input = well.toBigDecimal(); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } return calculate(aggregated); } /** * Returns the aggregated weighted statistic for each plate. * @param Collection collection of plates * @param double[] weights for the data set * @return map of plates and aggregated results */ public Map platesAggregated( Collection collection, double[] weights) { Preconditions.checkNotNull(collection, "The plate collection cannot be null."); Map results = new TreeMap(); for(Plate plate : collection) { List aggregated = new ArrayList(); Plate clone = new Plate(plate); for (Well well : plate) { List input = well.toBigDecimal(); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /** * Returns the aggregated weighted statistic for each plate. * @param PlateBigInteger[] array of plates * @param double[] weights for the data set * @return map of plates and aggregated results */ public Map platesAggregated( Plate[] array, double[] weights) { Preconditions.checkNotNull(array, "The plate array cannot be null."); Map results = new TreeMap(); for(Plate plate : array) { List aggregated = new ArrayList(); Plate clone = new Plate(plate); for (Well well : plate) { List input = well.toBigDecimal(); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /** * Returns the aggregated weighted statistic for the plate using the values * between the indices. * @param Plate the plate * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return the aggregated result */ public BigDecimal platesAggregated(Plate plate, double[] weights, int begin, int length) { Preconditions.checkNotNull(plate, "The plate cannot be null."); List aggregated = new ArrayList(); for (Well well : plate) { List input = well.toBigDecimal().subList(begin, begin + length); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } return calculate(aggregated); } /** * Returns the aggregated weighted statistic for each plate using the values * between the indices. * @param Collection collection of plates * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return map of plates and aggregated results */ public Map platesAggregated( Collection collection, double[] weights, int begin, int length) { Preconditions.checkNotNull(collection, "The plate collection cannot be null."); Map results = new TreeMap(); for(Plate plate : collection) { List aggregated = new ArrayList(); Plate clone = new Plate(plate); for (Well well : plate) { List input = well.toBigDecimal().subList(begin, begin + length); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /** * Returns the aggregated weighted statistic for each plate using the values * between the indices. * @param PlateBigInteger[] array of plates * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return map of plates and aggregated results */ public Map platesAggregated( Plate[] array, double[] weights, int begin, int length) { Preconditions.checkNotNull(array, "The plate array cannot be null."); Map results = new TreeMap(); for(Plate plate : array) { List aggregated = new ArrayList(); Plate clone = new Plate(plate); for (Well well : plate) { List input = well.toBigDecimal().subList(begin, begin + length); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /* --------------- Well statistics for all wells in a set -------------- */ /** * Returns the weighted statistic of each well in the well set. * @param WellSet the well set * @param double[] weights for the data set * @return map of wells and results */ public Map set(WellSet set, double[] weights) { Preconditions.checkNotNull(set, "The set cannot be null."); Map result = new TreeMap(); for (Well well : set) { Well clone = new Well(well); result.put(clone, well(well, weights)); } return result; } /** * Returns the weighted statistic of each well in the well set using the values * between the beginning and ending indices. * @param WellSet the well set * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return map of wells and results */ public Map set(WellSet set, double[] weights, int begin, int length) { Preconditions.checkNotNull(set, "The well set cannot be null."); Map result = new TreeMap(); for (Well well : set) { Well clone = new Well(well); result.put(clone, well(well, weights, begin, length)); } return result; } /* --------------------- Aggregated set statistics --------------------- */ /** * Returns the aggregated weighted statistic for the well set. * @param WellSet the well set * @param double[] weights for the data set * @return the aggregated results */ public BigDecimal setsAggregated(WellSet set, double[] weights) { Preconditions.checkNotNull(set, "The well set cannot be null."); Preconditions.checkNotNull(weights, "Weights array cannot be null."); List aggregated = new ArrayList(); for (Well well : set) { List input = well.toBigDecimal(); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } return calculate(aggregated); } /** * Returns the aggregated weighted statistic for each well set. * @param Collection collection of well sets * @param double[] weights for the data set * @return map of well sets and aggregated results */ public Map setsAggregated( Collection collection, double[] weights) { Preconditions.checkNotNull(collection, "The well set collection cannot be null."); Map results = new TreeMap(); for(WellSet set : collection) { List aggregated = new ArrayList(); WellSet clone = new WellSet(set); for (Well well : set) { List input = well.toBigDecimal(); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /** * Returns the aggregated weighted statistic for each well set. * @param WellSetBigInteger[] array of well sets * @param double[] weights for the data set * @return map of well sets and aggregated results */ public Map setsAggregated( WellSet[] array, double[] weights) { Preconditions.checkNotNull(array, "The well set array cannot be null."); Map results = new TreeMap(); for(WellSet set : array) { List aggregated = new ArrayList(); WellSet clone = new WellSet(set); for (Well well : set) { List input = well.toBigDecimal(); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /** * Returns the aggregated weighted statistic for the well set using the values * between the indices. * @param WellSet the well set * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return the aggregated result */ public BigDecimal setsAggregated(WellSet set, double[] weights, int begin, int length) { Preconditions.checkNotNull(set, "The well set cannot be null."); List aggregated = new ArrayList(); for (Well well : set) { List input = well.toBigDecimal().subList(begin, begin + length); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } return calculate(aggregated); } /** * Returns the aggregated weighted statistic for each well set using the values * between the indices. * @param Collection collection of well sets * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return map of well sets and aggregated results */ public Map setsAggregated( Collection collection, double[] weights, int begin, int length) { Preconditions.checkNotNull(collection, "The well set collection cannot be null."); Map results = new TreeMap(); for(WellSet set : collection) { List aggregated = new ArrayList(); WellSet clone = new WellSet(set); for (Well well : set) { List input = well.toBigDecimal().subList(begin, begin + length); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /** * Returns the aggregated weighted statistic for each well set using the values * between the indices. * @param WellSetBigInteger[] array of well sets * @param double[] weights for the data set * @param int beginning index of subset * @param int length of subset * @return map of well sets and aggregated results */ public Map setsAggregated( WellSet[] array, double[] weights, int begin, int length) { Preconditions.checkNotNull(array, "The well set array cannot be null."); Map results = new TreeMap(); for(WellSet set : array) { List aggregated = new ArrayList(); WellSet clone = new WellSet(set); for (Well well : set) { List input = well.toBigDecimal().subList(begin, begin + length); for(int i = 0; i < input.size(); i++) { aggregated.add(input.get(i).multiply(new BigDecimal(weights[i]))); } } results.put(clone, calculate(aggregated)); } return results; } /* -------------------------- Well statistics -------------------------- */ /** * Returns the weighted well statistic. * @param Well the well * @param double[] weights for the data set * @return the result */ public BigDecimal well(Well well, double[] weights) { Preconditions.checkNotNull(well, "The well cannot be null."); Preconditions.checkNotNull(weights, "The weights array cannot be null."); return calculate(well.toBigDecimal(), weights); } /** * Returns the well weighted statistic for the values between the beginning and * ending indices. * @param Well the well * @param double[] weights for the data set * @param int beginning index of subset * @param int length of the subset * @return the result */ public BigDecimal well(Well well, double[] weights, int begin, int length) { Preconditions.checkNotNull(well, "The well cannot be null."); Preconditions.checkNotNull(weights, "The weights array cannot be null."); Preconditions.checkArgument(begin <= well.toBigDecimal().size() && begin >= 0 && begin + length <= well.toBigDecimal().size()); return calculate(well.toBigDecimal(), weights, begin, length); } /* -------- Methods for calculating the statistic of a data set -------- */ /** * Calculates the weighted statistic. * @param List the list * @param double[] weights for the data set * @return the result */ public abstract BigDecimal calculate(List list, double[] weights); /** * Calculates the weighted statistic of the values between the beginning and * ending indices. * @param List the list * @param double[] weights of the data set * @param int beginning index of subset * @param int length of subset * @return the result */ public abstract BigDecimal calculate(List list, double[] weights, int begin, int length); }




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