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/**
 * ****************************************************************************
 * Copyright 2013 EMBL-EBI
 * 

* Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at *

* http://www.apache.org/licenses/LICENSE-2.0 *

* Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * **************************************************************************** */ package htsjdk.samtools.cram.build; final public class Utils { private Utils() {}; /** * CRAM operates with upper case bases, so both read and ref bases should be * upper-cased and vocab controlled. This method does exactly this: upper * case acgt and replace everything else with N. * * @param base a base to normalize * @return a normalized base */ public static byte normalizeBase(final byte base) { switch (base) { case 'a': case 'A': return 'A'; case 'c': case 'C': return 'C'; case 'g': case 'G': return 'G'; case 't': case 'T': return 'T'; default: return 'N'; } } }





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