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/*
* Copyright or © or Copr. Ecole des Mines d'Alès (2012-2014)
*
* This software is a computer program whose purpose is to provide
* several functionalities for the processing of semantic data
* sources such as ontologies or text corpora.
*
* This software is governed by the CeCILL license under French law and
* abiding by the rules of distribution of free software. You can use,
* modify and/ or redistribute the software under the terms of the CeCILL
* license as circulated by CEA, CNRS and INRIA at the following URL
* "http://www.cecill.info".
*
* As a counterpart to the access to the source code and rights to copy,
* modify and redistribute granted by the license, users are provided only
* with a limited warranty and the software's author, the holder of the
* economic rights, and the successive licensors have only limited
* liability.
* In this respect, the user's attention is drawn to the risks associated
* with loading, using, modifying and/or developing or reproducing the
* software by the user in light of its specific status of free software,
* that may mean that it is complicated to manipulate, and that also
* therefore means that it is reserved for developers and experienced
* professionals having in-depth computer knowledge. Users are therefore
* encouraged to load and test the software's suitability as regards their
* requirements in conditions enabling the security of their systems and/or
* data to be ensured and, more generally, to use and operate it in the
* same conditions as regards security.
*
* The fact that you are presently reading this means that you have had
* knowledge of the CeCILL license and that you accept its terms.
*/
package slib.examples.sml.go;
import java.util.Set;
import org.openrdf.model.URI;
import org.openrdf.model.vocabulary.OWL;
import slib.graph.algo.accessor.GraphAccessor;
import slib.graph.algo.utils.GAction;
import slib.graph.algo.utils.GActionType;
import slib.graph.io.conf.GDataConf;
import slib.graph.io.conf.GraphConf;
import slib.graph.io.loader.GraphLoaderGeneric;
import slib.graph.io.util.GFormat;
import slib.graph.model.graph.G;
import slib.graph.model.impl.repo.URIFactoryMemory;
import slib.graph.model.repo.URIFactory;
import slib.sml.sm.core.utils.SMConstants;
import slib.sml.sm.core.engine.SM_Engine;
import slib.sml.sm.core.metrics.ic.utils.IC_Conf_Corpus;
import slib.sml.sm.core.metrics.ic.utils.ICconf;
import slib.utils.ex.SLIB_Exception;
/**
*
* Example which shows how to use the Semantic Measures Library to compute
* the Information Content (IC) of Gene Ontology terms using an Extrinsic IC
* (e.g. using Resnik IC).
*
* In this snippet we compute the IC of the GO terms defined in the
* Gene Ontology using Resnik IC formulation
*
* More information at http://www.semantic-measures-library.org/
*
*
* @author Sébastien Harispe
*/
public class SMComputationGO_extrinsic_IC {
public static void main(String[] params) throws SLIB_Exception {
// The input files.
// - The Gene Ontology (OBO format)
// - Annotations (GAF2)
String goOBO = "/data/go/gene_ontology_ext.obo";
String annot = "/data/go/gene_association.goa_human";
URIFactory factory = URIFactoryMemory.getSingleton();
URI graph_uri = factory.getURI("http://go/");
// We define a prefix in order to build valid uris from ids such as GO:XXXXX,
// considering the configuration specified below the URI associated
// to GO:XXXXX will be http://go/XXXXX
factory.loadNamespacePrefix("GO", graph_uri.toString());
// We configure the graph
GraphConf graphConf = new GraphConf(graph_uri);
graphConf.addGDataConf(new GDataConf(GFormat.OBO, goOBO));
graphConf.addGDataConf(new GDataConf(GFormat.GAF2, annot));
GAction rooting = new GAction(GActionType.REROOTING);
rooting.addParameter("root_uri", OWL.THING.stringValue());
graphConf.addGAction(rooting);
G graph = GraphLoaderGeneric.load(graphConf);
// General information about the graph
System.out.println(graph.toString());
// We retrieve only the classes, i.e. GO terms
// Note that the graph also contains the genes
Set goTerms = GraphAccessor.getClasses(graph);
System.out.println("GO terms : " + goTerms.size());
// We configure the IC
ICconf icConfRes = new IC_Conf_Corpus(SMConstants.FLAG_IC_ANNOT_RESNIK_1995);
SM_Engine engine = new SM_Engine(graph);
for (URI goTerm : goTerms) {
System.out.println(goTerm + "\t" + engine.getIC(icConfRes,goTerm));
}
}
}