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        Item #
        Length
        Source of Standard
        Year Implemented
        Version Implemented
        Year Retired
        Version Retired
    
    
        3938
        1
        NAACCR
        2021
        21
        
        
    



NAACCR XML: Tumor.alkRearrangement




Description
Testing for ALK rearrangement is performed for patients with advanced non-small cell lung cancer (NSCLC) to identify tumors which are sensitive to small-molecule ALK kinase inhibitors.
Rationale
ALK rearrangement is recommended by treatment guidelines for patients with advanced lung cancer as a prognostic marker and factor in determining appropriate therapy. It is a new data item for cases diagnosed 01/01/2021+.
Codes

    
        
            0
            Normal

                ALK negative

                Negative for rearrangement, no rearrangement identified, no mutations (somatic) identified, not present, not detected


            
        
        
            1
            Abnormal Rearrangement identified/detected: EML4-ALK, KIF5B-ALK, TFG-ALK, and/or KLC1-ALK
        
        
            2
            Rearrangement identified/detected: Other ALK Rearrangement not listed in code 1
        
        
            4
            Rearrangement, NOS
        
        
            7
            Test ordered, results not in chart
        
        
            8
            Not applicable: Information not collected for this case

                If this information is required by your standard setter, use of code 8 may result in an edit error.
            
        
        
            9
            Not documented in medical record

                ALK Rearrangement not assessed or unknown if assessed
            
        
        
            Blank
            Diagnosis year is prior to 2021
        
        
            
        
    

Each Site-Specific Data Item (SSDI) applies only to selected primary
    sites, histologies, and years of diagnosis. Depending on applicability
    and standard-setter requirements, SSDIs may be left blank.

0	Normal ALK negative Negative for rearrangement, no rearrangement identified, no mutations (somatic) identified, not present, not detected
1	Abnormal Rearrangement identified/detected: EML4-ALK, KIF5B-ALK, TFG-ALK, and/or KLC1-ALK
2	Rearrangement identified/detected: Other ALK Rearrangement not listed in code 1
4	Rearrangement, NOS
7	Test ordered, results not in chart
8	Not applicable: Information not collected for this case If this information is required by your standard setter, use of code 8 may result in an edit error.
9	Not documented in medical record ALK Rearrangement not assessed or unknown if assessed
Blank	Diagnosis year is prior to 2021