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{
"id" : "nodes_daj",
"algorithm" : "cs",
"version" : "02.05.50",
"name" : "Nodes",
"title" : "CS Lymph Nodes",
"notes" : "**Note 1**: Code only regional nodes and nodes, NOS, in this field. Distant nodes such as cervical (excluding supraclavicular) or contralateral axillary are coded in CS Mets at DX.\n\n**Note 2**: Micrometastases are defined as tumor deposits greater than 0.2 millimeter (mm) but not greater than 2.0 mm in largest dimension. Macrometastases are tumor deposits greater than 2.0 mm. All nodes with at least micrometastases are included in the count of positive lymph nodes, but at least one node must contain a macrometastasis for assignment of a pathologic N category greater than pN1mi.\n\n**Note 3**: If the pathology report indicates that nodes are positive but size of the metastases is not stated, assume the metastases are greater than 0.2 mm and code the lymph nodes as positive in this field. Use code 600 in the absence of other information about regional nodes.\n\n**Note 4**: In a physical exam if palpable nodes are not described as fixed or matted, assume that nodes are movable.\n\n**Note 5**: Codes 130-600 refer to level I and level II ipsilateral axillary lymph nodes and ipsilateral intramammary nodes only. Ipsilateral level III axillary lymph nodes, which are also known as infraclavicular or apical nodes, are coded 750 or higher. Axillary lymph nodes do not include internal mammary or ipsilateral supraclavicular lymph nodes.\n\n**Note 6**: For the breast schema, the choice of the N category is dependent on the CS Lymph Nodes Eval field. There are certain CS Lymph Nodes codes that can only be used if the nodes are evaluated clinically (CS Lymph Nodes Eval is coded 0, 1, 5, or 9), which will be designated as \"Evaluated clinically:\" at the beginning of the code description. Similarly, there are certain CS Lymph Nodes codes that can only be used if the nodes are evaluated pathologically (CS Lymph Nodes Eval is coded 2, 3, 6, or 8), and these will be designated as \"Evaluated pathologically:\". All other codes can be used for clinical or pathologic evaluation.\n\n**Note 7**: Isolated tumor cells (ITC) are defined as single tumor cells or small clusters not greater than 0.2 mm, usually detected only by immunohistochemical (IHC) or molecular methods but which may be verified on hematoxylin and eosin (H and E) stains. ITCs do not usually show evidence of malignant activity (e.g., proliferation or stromal reaction). Lymph nodes with ITCs only are not considered positive lymph nodes. If the record only states N0(i+), code to 000 and see CS Site-Specific Factor 4.",
"footnotes" : "- For CS Lymph Nodes code 000 ONLY, the N category is assigned based on the coding of CS Site-Specific Factors 4 and 5 using the IHC MOL Table for this schema.\n- For CS Lymph Nodes codes 250, 258, 260, 510, 520, 600, 610, 620, 630, 720, and 748 ONLY, the N category is assigned based on the values of CS Lymph Nodes Eval and CS Site-Specific Factor 3 (Number of Positive Ipsilateral Axillary Lymph Nodes). If the CS Lymph Nodes Eval code is 2 (p), 3 (p), 6 (yp), or 8 (a), the N category is determined by reference to the Lymph Nodes Pathologic Evaluation Table. If the CS Lymph Nodes Eval code is 0 (c), 1(c), 5(c), or 9 (c), the N category is determined by reference to the Lymph Nodes Clinical Evaluation Table. If the CS Lymph Nodes Eval field is not coded, the N category is determined by reference to the Lymph Nodes Positive Axillary Node Table.\n- For CS Lymph Nodes code 000 ONLY, the N category is assigned based on the coding of CS Site-Specific Factors 4 and 5 using the IHC MOL Table for this schema.\n- For CS Lymph Nodes codes 250,258, 260, 280, 500, 510, 520, 600, 610, 620, 630, 720, and 748 ONLY, the N category is assigned based on the values of CS Lymph Nodes Eval and CS Site-Specific Factor 3 (Number of Positive Ipsilateral Axillary Lymph Nodes). If the CS Lymph Nodes Eval code is 2 (p), 3 (p), 6 (yp), or 8 (a), the N category is determined by reference to the Lymph Nodes Pathologic Evaluation Table. If the CS Lymph Nodes Eval code is 0 (c), 1(c), 5(c), or 9 (c), the N category is determined by reference to the Lymph Nodes Clinical Evaluation Table. If the CS Lymph Nodes Eval field is not coded, the N category is determined by reference to the Lymph Nodes Positive Axillary Node Table.",
"last_modified" : "2015-05-27T16:19:31.857Z",
"definition" : [ {
"key" : "nodes",
"name" : "Code",
"type" : "INPUT"
}, {
"key" : "description",
"name" : "Description",
"type" : "DESCRIPTION"
}, {
"key" : "ajcc7_n",
"name" : "AJCC 7 N",
"type" : "ENDPOINT"
}, {
"key" : "ajcc6_n",
"name" : "TNM 6 N",
"type" : "ENDPOINT"
}, {
"key" : "n77",
"name" : "Summary Stage 1977 N",
"type" : "ENDPOINT"
}, {
"key" : "n2000",
"name" : "Summary Stage 2000 N",
"type" : "ENDPOINT"
} ],
"rows" : [ [ "000", "No regional lymph node involvement \nOR isolated tumor cells (ITCs) detected by immunohistochemistry/immunohistochemical (IHC) methods or molecular methods ONLY. \n(See Note 7 and CS Site-Specific Factors 4 and 5)", "JUMP:ihcmol_xcc", "JUMP:ihcmol_xcc", "VALUE:NONE", "VALUE:NONE" ], [ "050", "Evaluated pathologically:\n\nNone; no regional lymph node involvement \nBUT ITCs detected on routine hematoxylin and eosin (H and E) stains. \n(See Note 7)", "VALUE:N0(i+)", "VALUE:N0(i+)", "VALUE:NONE", "VALUE:NONE" ], [ "130", "Evaluated pathologically:\n\nAxillary lymph node(s), ipsilateral, micrometastasis ONLY detected by IHC ONLY \n(At least one micrometastasis greater than 0.2 mm or more than 200 cells \nAND all micrometastases less than or equal to 2 mm)", "VALUE:N1mi", "VALUE:N1mi", "VALUE:RN", "VALUE:RN" ], [ "150", "Evaluated pathologically:\n\nAxillary lymph node(s), ipsilateral, micrometastasis ONLY detected or verified on H&E \n(At least one micrometastasis greater than 0.2 mm or more than 200 cells \nAND all micrometastases less than or equal to 2 mm)\n\nMicrometastasis, NOS", "VALUE:N1mi", "VALUE:N1mi", "VALUE:RN", "VALUE:RN" ], [ "155", "Evaluated pathologically:\n\nStated as N1mi with no other information on regional lymph nodes", "VALUE:N1mi", "VALUE:N1mi", "VALUE:RN", "VALUE:RN" ], [ "250", "Evaluated pathologically:\n\nMovable axillary lymph node(s), ipsilateral, positive with more than micrometastasis \n(At least one metastasis greater than 2 mm) \n(See Note 4)", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "255", "Evaluated clinically:\n\nClinically movable axillary lymph node(s), ipsilateral, positive \n(Clinical assessment because of neoadjuvant therapy or no pathology) \n(See Note 4)", "VALUE:N1", "VALUE:N1", "VALUE:RN", "VALUE:RN" ], [ "257", "Evaluated clinically:\n\nClinically stated only as N1 \n(Clinical assessment because of neoadjuvant therapy or no pathology)", "VALUE:N1", "VALUE:N1", "VALUE:RN", "VALUE:RN" ], [ "258", "Evaluated pathologically:\n\nPathologically stated only as N1 [NOS], no information on which nodes were involved ", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "260", "Stated as N1 [NOS] with no other information on regional lymph nodes", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "280", "OBSOLETE DATA RETAINED V0104\n\nStated as N2, NOS", "ERROR:", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "290", "OBSOLETE DATA CONVERTED V0203\nSee code 610\n\nClinically stated only as N2, NOS (clinical assessment because of neoadjuvant therapy or no pathology)", "ERROR:", "ERROR:", "ERROR:", "ERROR:" ], [ "300", "OBSOLETE DATA CONVERTED V0203\nSee code 620\n\nPathologically stated only as N2 NOS; no information on which nodes were involved", "ERROR:", "ERROR:", "ERROR:", "ERROR:" ], [ "500", "OBSOLETE DATA RETAINED V0104\n\nFixed/matted ipsilateral axillary nodes, positive with more than micrometastasis (i.e., at least one metastasis greater than 2 mm)\n\nFixed/matted ipsilateral axillary nodes, NOS", "ERROR:", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "510", "Evaluated clinically:\n\nFixed/matted ipsilateral axillary nodes clinically \n(Clinical assessment because of neoadjuvant therapy or no pathology)\n\nStated clinically as N2a (Clinical assessment because of neoadjuvant therapy or no pathology)", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "520", "Evaluated pathologically:\n\nFixed/matted ipsilateral axillary nodes clinically with pathologic involvement of lymph nodes\nWITH at least one metastasis greater than 2 mm", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "600", "Axillary/regional lymph node(s), NOS\nLymph nodes, NOS", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "610", "Evaluated clinically:\n\nClinically stated only as N2 [NOS] \n(Clinical assessment because of neoadjuvant therapy or no pathology)", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "620", "Evaluated pathologically:\n\nPathologically stated only as N2 [NOS]; no information on which nodes were involved", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "630", "Stated as N2 [NOS] with no other information on regional lymph nodes", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "710", "Evaluated pathologically:\n\nInternal mammary node(s), ipsilateral, positive on sentinel nodes but not clinically apparent \n(No positive imaging or clinical exam)\nWITHOUT axillary lymph node(s), ipsilateral", "VALUE:N1b", "VALUE:N1b", "VALUE:RN", "VALUE:RN" ], [ "720", "Evaluated pathologically:\n\nInternal mammary node(s), ipsilateral, positive on sentinel nodes but not clinically apparent \n(No positive imaging or clinical exam)\nWITH axillary lymph node(s), ipsilateral", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "730", "Evaluated pathologically:\n\nInternal mammary node(s), ipsilateral, positive on sentinel nodes but not clinically apparent \n(No positive imaging or clinical exam)\nUNKNOWN if positive axillary lymph node(s), ipsilateral", "VALUE:N1b", "VALUE:N1b", "VALUE:RN", "VALUE:RN" ], [ "735", "Evaluated clinically:\n\nInternal mammary node(s), ipsilateral, positive on sentinel nodes but primary not resected\nWITHOUT axillary lymph node(s), ipsilateral OR UNKNOWN if positive axillary lymph node(s),", "VALUE:N2b", "VALUE:N2b", "VALUE:RN", "VALUE:RN" ], [ "740", "Internal mammary node(s), ipsilateral, clinically apparent \n(On imaging or clinical exam)\nWITHOUT axillary lymph node(s), ipsilateral", "VALUE:N2b", "VALUE:N2b", "VALUE:RN", "VALUE:RN" ], [ "745", "Internal mammary node(s), ipsilateral, clinically apparent \n(On imaging or clinical exam) \nUNKNOWN if positive axillary lymph node(s), ipsilateral", "VALUE:N2b", "VALUE:N2b", "VALUE:RN", "VALUE:RN" ], [ "748", "Stated as N2b with no other information on regional lymph nodes", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "JUMP:determine_correct_table_for_ajcc6_n_ns9", "VALUE:RN", "VALUE:RN" ], [ "750", "Infraclavicular lymph node(s)(subclavicular) (level III axillary nodes) (apical), ipsilateral\nWITH or WITHOUT axillary nodes(s)\nWITHOUT internal mammary node(s)", "VALUE:N3a", "VALUE:N3a", "VALUE:D", "VALUE:RN" ], [ "755", "Stated as N3a with no other information on regional lymph nodes", "VALUE:N3a", "VALUE:N3a", "VALUE:D", "VALUE:RN" ], [ "760", "OBSOLETE DATA RETAINED AND REVIEWED V0203\nSee codes 763 and765\n\nInternal mammary node(s), ipsilateral, clinically apparent (on imaging or clinical exam)\nWITH axillary lymph node(s), ipsilateral, codes 150 to 600\nWITH or WITHOUT infraclavicular (level III axillary nodes) (apical) lymph nodes", "VALUE:N3b", "VALUE:N3b", "VALUE:RN", "VALUE:RN" ], [ "763", "Internal mammary node(s), ipsilateral, clinically apparent \n(On imaging or clinical exam)\nWITH axillary lymph node(s), ipsilateral, codes 150 to 600\nWITHOUT infraclavicular (level III axillary nodes) (apical) lymph nodes or unknown if infraclavicular (level III axillary nodes) (apical) lymph nodes involved", "VALUE:N3b", "VALUE:N3b", "VALUE:RN", "VALUE:RN" ], [ "764", "Internal mammary node(s), ipsilateral, clinically apparent \n(On imaging or clinical exam)\nWITHOUT axillary lymph node(s), ipsilateral\nWITH infraclavicular (level III axillary nodes) (apical) lymph nodes involved", "VALUE:N3b", "VALUE:N3b", "VALUE:D", "VALUE:RN" ], [ "765", "Internal mammary node(s), ipsilateral, clinically apparent \n(On imaging or clinical exam)\nWITH axillary lymph node(s), ipsilateral\nWITH infraclavicular (level III axillary nodes) (apical) lymph nodes involved\n", "VALUE:N3b", "VALUE:N3b", "VALUE:D", "VALUE:RN" ], [ "768", "Stated as N3b with no other information on regional lymph nodes", "VALUE:N3b", "VALUE:N3b", "VALUE:RN", "VALUE:RN" ], [ "770", "OBSOLETE DATA RETAINED V0200 \n\nInternal mammary node(s), ipsilateral, clinically apparent (on imaging or clinical exam)\nUNKNOWN if positive axillary lymph node(s), ipsilateral", "ERROR:", "VALUE:N2b", "VALUE:RN", "VALUE:RN" ], [ "780", "OBSOLETE DATA RETAINED V0200 \n\n(750) + (770)", "ERROR:", "VALUE:N3a", "VALUE:D", "VALUE:RN" ], [ "790", "OBSOLETE DATA CONVERTED V0203\nSee code 820\n\nStated as N3, NOS", "ERROR:", "ERROR:", "ERROR:", "ERROR:" ], [ "800", "Supraclavicular node(s), ipsilateral", "VALUE:N3c", "VALUE:N3c", "VALUE:D", "VALUE:D" ], [ "805", "Stated as N3c with no other information on regional lymph nodes", "VALUE:N3c", "VALUE:N3c", "VALUE:D", "VALUE:D" ], [ "810", "Evaluated clinically:\n\nClinically stated only as N3 [NOS] \n(Clinical assessment because of neoadjuvant therapy or no pathology)", "VALUE:N3NOS", "VALUE:N3NOS", "VALUE:RN", "VALUE:RN" ], [ "815", "Evaluated pathologically:\n\nPathologically stated only as N3 [NOS]; no information on which nodes were involved", "VALUE:N3NOS", "VALUE:N3NOS", "VALUE:RN", "VALUE:RN" ], [ "820", "Stated as N3, NOS with no other information on regional lymph nodes", "VALUE:N3NOS", "VALUE:N3NOS", "VALUE:RN", "VALUE:RN" ], [ "999", "Unknown; regional lymph nodes not stated\nRegional lymph node(s) cannot be assessed\nNot documented in patient record", "VALUE:NX", "VALUE:NX", "VALUE:U", "VALUE:U" ] ]
}
