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{
"id" : "extension_bbb",
"algorithm" : "eod_public",
"version" : "1.0",
"name" : "EOD Primary Tumor",
"title" : "EOD Primary Tumor",
"notes" : "**Note 1:** The wall of the esophagus has five layers: mucosal (code 100), submucosal (code 200), muscular (code 250), subserosal (code 300) and serosal (code 400). \n* The three layers of the mucosa (epithelium, lamina propria, and muscularis mucosae) may be called the m1, m2, and m3 layers. The submucosa may be described as having inner, middle, and outer thirds called sm1, sm2, and sm3.\n\n**Note 2:** Non-invasive carcinomas in the esophagus formerly called in situ are now called high grade dysplasia. High grade dysplasia and severe dysplasia are generally not reportable in cancer registries. \n* Code 000 if your registry collects these tumors\n\n**Note 3:** Ignore intraluminal extension to adjacent segment(s) of esophagus or to cardia of stomach and code depth of invasion or extra-esophageal spread as indicated.\n\n**Note 4:** If the tumor's extension is only described by a phrase like \"through the muscularis propria\", this could mean that the cancer has penetrated the outermost muscle cells but not beyond (code 250); but usually \"through the muscularis\" or “through the esophageal wall” is used to indicate that the cancer extends beyond the muscle and into adjacent tissue (code 300).",
"footnotes" : "(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998\n\n(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.\n\n(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)\n\n(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30\n\n(5) Rice, T.W., Kelsen, D., Hofstetter, W.L., et al. **Esophagus and Esophagogastric Junction**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 185-202",
"last_modified" : "2018-03-12T16:39:56.809Z",
"definition" : [ {
"key" : "eod_primary_tumor",
"name" : "Code",
"type" : "INPUT"
}, {
"key" : "description",
"name" : "Description",
"type" : "DESCRIPTION"
}, {
"key" : "eod_2018_t",
"name" : "EOD 2018 T",
"type" : "ENDPOINT"
}, {
"key" : "ss2018_t",
"name" : "SS2018 T",
"type" : "ENDPOINT"
} ],
"rows" : [ [ "000", "In situ, intraepithelial, non-invasive, high-grade dysplasia\n(Adeno)carcinoma, noninvasive, in a polyp", "VALUE:Tis", "VALUE:IS" ], [ "100", "Intramucosal, NOS\nLamina propria\nMucosa, NOS\nMuscularis mucosae", "VALUE:T1a", "VALUE:L" ], [ "150", "Submucosa (superficial invasion)", "VALUE:T1b", "VALUE:L" ], [ "200", "Confined to esophagus, NOS\n\nLocalized, NOS", "VALUE:T1", "VALUE:L" ], [ "250", "Muscularis propria", "VALUE:T2", "VALUE:L" ], [ "300", "Extension through wall, NOS \nInvasion through muscularis propria or muscularis, NOS\nPerimuscular tissue invaded\nSubserosal tissue/(sub)serosal fat invaded", "VALUE:T3", "VALUE:L" ], [ "350", "Adventitia and/or soft tissue invaded\nEsophagus is described as \"FIXED\"\n\nExtension to adjacent (connective) tissue \nWITHOUT perforation of visceral peritoneum covering these structures\nGastric artery\nLigaments\n- Gastrocolic\n- Gastrohepatic\n- Gastrosplenic\n- Omentum (greater, lesser, NOS)\n\nPerigastric fat", "VALUE:T3", "VALUE:RE" ], [ "400", "All subsites\n- Azygos vein\n- Diaphragm (excluding abdominal/lower esophagus, see code 500)\n- Mesothelium\n- Pericardium (excluding thoracic/middle esophagus, see code 500)\n- Peritoneum, NOS\n- Pleura (excluding cervical/upper esophagus, see code 500)\n- Serosa (invasion of/or through)\n- Tunica serosa\n- Visceral peritoneum (including perforation)\n\nCervical esophagus\n- Hypopharynx\n- Jugular vein\n- Larynx\n- Thyroid gland \n\nIntrathoracic esophagus, lower portion (abdominal)\n- Blood vessel(s), major\n + Gastric artery/vein\n- Stomach, cardia (via serosa)", "VALUE:T4a", "VALUE:RE" ], [ "500", "Abdominal/lower esophagus\n- Diaphragm fixed \n\nCervical/upper esophagus\n- Pleura \n\nThoracic/middle esophagus\n- Pericardium\n\nEsophagus GE Junction \n- Abdominal wall\n- Adrenal (suprarenal) gland\n- Kidney\n- Retroperitoneum", "VALUE:T4a", "VALUE:D" ], [ "600", "All subsites\n- Adjacent structure(s), NOS\n- Aorta \n\nCervical esophagus\n- Blood vessel(s)\n + Carotid artery \n + Subclavian artery\n- Carina \n- Cervical vertebra(e) \n- Trachea \n\nIntrathoracic, upper or mid-portion, esophagus\n- Blood vessel(s), major\n + Pulmonary artery/vein \n + Vena cava \n- Carina \n- Trachea\n\nIntrathoracic, lower portion (abdominal), esophagus\n- Blood vessel(s)\n + Vena cava \n\nIntrathoracic esophagus (all portions)\n- Adjacent rib(s) \n- Lung via bronchus\n- Mediastinal structure(s), NOS \n- Thoracic vertebra(e)\n\nEsophagus GE Junction\n- Liver\n- Pancreas\n- Small intestine (duodenum [via serosa], ileum, jejunum)\n- Spleen\n- Transverse colon (including flexures)", "VALUE:T4b", "VALUE:RE" ], [ "700", "All subsites\n- Airway\n- Vertebral body\n\nCervical/upper esophagus\n- Lung\n- Mainstem bronchus\n\nEsophagus GE Junction\n- Trachea\n\nStated as unresectable, NOS\n\nFurther contiguous extension", "VALUE:T4b", "VALUE:D" ], [ "800", "No evidence of primary tumor", "VALUE:T0", "VALUE:U" ], [ "999", "Unknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in patient record\n\nDeath Certificate Only", "VALUE:TX", "VALUE:U" ] ]
}
