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{
"id" : "grade_post_therapy_32342",
"algorithm" : "eod_public",
"version" : "1.0",
"name" : "Grade Post Therapy",
"title" : "Grade Post Therapy",
"notes" : "**Note 1:** Leave post-therapy grade blank when\n* No neoadjuvant therapy\n* Clinical or pathological case only\n* There is only one grade available and it cannot be determined if it is clinical, pathological or post-therapy\n\n**Note 2:** Assign the highest grade from the resected primary tumor assessed after the completion of neoadjuvant therapy.\n\n**Note 3:** Codes L and H take priority over A-D. \n\n**Note 4:** Code 9 when \n* Surgical resection is done after neoadjuvant therapy and grade from the primary site is not documented\n* Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available",
"last_modified" : "2018-03-12T16:39:59.700Z",
"definition" : [ {
"key" : "grade_post_therapy",
"name" : "Code",
"type" : "INPUT"
}, {
"key" : "description",
"name" : "Description",
"type" : "DESCRIPTION"
} ],
"rows" : [ [ "L", "LG: Low grade: round monomorphic nuclei with only mild to moderate nuclear size variation, indistinct nucleoli, and chromatin characteristics resembling those of normal parathyroid or of adenoma" ], [ "H", "HG: High grade: more pleomorphism, with a nuclear size variation greater than 4:1; prominent nuclear membrane irregularities; chromatin alterations, including hyperchromasia or margination of chromatin; and prominent nucleoli. High-grade tumors show several discrete confluent areas with nuclear changes" ], [ "A", "Well differentiated" ], [ "B", "Moderately differentiated" ], [ "C", "Poorly differentiated" ], [ "D", "Undifferentiated, anaplastic" ], [ "9", "Grade cannot be assessed (GX); Unknown" ], [ "", "See Note 1" ] ]
}