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{
"id" : "clin_m_hch",
"algorithm" : "tnm",
"version" : "1.6",
"name" : "Clin M GIST Appendix",
"title" : "Clinical M",
"notes" : "**Note 1:** Liver metastasis implies the presence of tumor inside the liver parenchyma as one or more nodules. \n* Do not code as liver metastasis when there is adherence to the liver capsule, even if extensive. For liver adherence, see T (primary tumor) \n\n**Note 2:** When a patient has more than one area of gastrointestinal stromal tumor (GIST), it is important to try to distinguish between intra-abdominal metastasis and tumor multiplicity. Distant metastases are relatively rare in GISTs, but they are increasingly detected with sophisticated radiological studies. Intra-abdominal metastasis will present as tumor involvement in the abdominal cavity outside the main tumor mass, in the peritoneum, omentum, serosae of organs, and the cul-de-sac, among other areas. \n* Assign this form of metastasis as cM1\n\n**Note 3:** Tumor multiplicity, in contrast, will present with anatomically separate, multiple tumors of different sizes arising independently in the GI tract. This form of tumor multiplicity usually will be seen in patients with neurofibromatosis type 1 or familial GIST syndrome, but in rare instances may be seen in patients without these conditions. This form of multiplicity should not be coded as metastasis, but the presence of multiple tumors should be coded in **Site-Specific Factor 15, Tumor Multiplicity**.\n* When a solitary omental or mesenteric tumor mass is found with a primary GIST elsewhere, do not code this as a metastasis. Code it as multiple tumors in **Site-Specific Factor 15, Tumor Multiplicity**\n* When multiple tumor areas are present and it is not stated whether these are metastases or independent tumors, consult with a physician if possible to determine how to code them. If a decision cannot be made, assign cM0 \n\n**Note 4:** Assign M1 for peritoneal nodules. \n\n**Note 5:** Superior and inferior mesenteric node(s) are included in M (distant metastasis). Mesenteric node(s), NOS are assigned in N (regional lymph nodes).\n\n**Distant lymph nodes**\n\n Inferior mesenteric lymph nodes\n Superior mesenteric lymph nodes",
"last_modified" : "2018-02-02T14:54:20.677Z",
"definition" : [ {
"key" : "clin_m",
"name" : "Clinical M",
"type" : "INPUT"
}, {
"key" : "clin_m_display",
"name" : "Clinical M Display",
"type" : "DESCRIPTION"
}, {
"key" : "description",
"name" : "Description",
"type" : "DESCRIPTION"
}, {
"key" : "notes",
"name" : "Registrar Notes",
"type" : "DESCRIPTION"
} ],
"rows" : [ [ "c0", "cM0", "No distant metastasis", "Unknown; distant metastasis not stated\nDistant metastasis cannot be assessed\nNot documented in patient record" ], [ "c1", "cM1", "Distant metastasis", "CLINICAL assessment only:\nDistant lymph nodes, NOS\n\nDistant metastasis including: \n Peritoneal nodules\n Liver parenchymal nodules\n\nCarcinomatosis\n\nDistant metastasis WITH or WITHOUT distant lymph node(s) \n\nDistant metastasis, NOS\n\nStated as M1" ], [ "p1", "pM1", "Distant metastasis", "HISTOLOGICALLY confirmed:\nDistant lymph nodes, NOS\n\nDistant metastasis including: \n Peritoneal nodules\n Liver parenchymal nodules\n\nCarcinomatosis\n\nDistant metastasis WITH or WITHOUT distant lymph node(s) \n\nDistant metastasis, NOS" ], [ "88", "88", "Not applicable", "In situ case but no pTis is defined by TNM\nDeath certificate only (DCO) case" ], [ "", "BLANK", "See Registrar Notes", "Clinical classification criteria not met \nClinical classification criteria met, evaluation done:\n No information about diagnostic workup\n Results not documented in patient record\nClinical evaluation of T and N not done, no evidence metastatic disease\nTumor first detected on surgical resection (no clinical workup)\nOnly Clinical Stage Group documented (no T, N, or M information available)" ] ]
}