algorithms.eod_public.1.1.tables.brain_molecular_markers_75370.json Maven / Gradle / Ivy
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A cancer staging client library
{
"id" : "brain_molecular_markers_75370",
"algorithm" : "eod_public",
"version" : "1.1",
"name" : "Brain Molecular Markers",
"title" : "Brain Molecular Markers",
"notes" : "**Note 1:** This data item applies only to ICD-O-3 histology codes: 9400/3, 9401/3, 9440/3, 9450/3, 9451/3, 9471/3 and 9478/3. If a histology is not included in this list, assign, code 85. \n\n**Note 2:** Physician statement of histologic subtype can be used to code this data item. \n\n**Note 3:** Only one code is applicable for each tumor. \n* IDH mutation status distinguishes between clinically important subtypes within ICD-O-3 9400/3, Diffuse astrocytoma and 9401/3, Anaplastic astrocytoma.\n* IDH mutant and 1p/19q co-deletion distinguishes between clinically important subtypes within ICD-O-3 code 9450/3, Oligodendroglioma and 9451/3, Anaplastic Oligodendroglioma.\n* IDH-wildtype distinguishes clinically important subtypes within ICD-O-3 9400/3, Diffuse astrocytoma, 9401/3, Anaplastic astrocytoma and 9440/3, Glioblastoma, Epithelioid glioblastoma and Glioblastoma, NOS (note that the new ICD-O-3 code 9445/3 applies to Glioblastoma, IDH-mutant; information regarding this subtype is not collected using this data item).\n* SHH-activation and TP53-wildtype distinguishes between clinically important subtypes within ICD-O-3 histology code 9471/3, Medulloblastoma. \n* C19MC alteration status distinguishes a clinically important highly aggressive subtype within ICD-O-3 9478/3, Embryonal tumor with multilayered rosettes.\n\n***Examples:***\n1.\tBiopsy of brain tumor, microscopic confirmation diagnosis: Diffuse Astrocytoma (9400/3). Additional testing done and IDH-mutant is identified. Code 01.\n2.\tBiopsy of brain tumor, microscopic confirmation diagnosis: Anaplastic astrocytoma (9401/3). No further testing or results unknown. Code 99.\n3.\tMRI of brain tumor, clinical diagnosis: glioblastoma. No further workup. Code 99.\n4.\tBiopsy of brain tumor, microscopic confirmation diagnosis: Mixed glioma (9382/3). Code 85.",
"last_modified" : "2018-04-19T21:51:26.909Z",
"definition" : [ {
"key" : "brain_molecular_markers",
"name" : "Code",
"type" : "INPUT"
}, {
"key" : "description",
"name" : "Description",
"type" : "DESCRIPTION"
} ],
"rows" : [ [ "01", "Diffuse astrocytoma, IDH-mutant (9400/3)" ], [ "02", "Diffuse astrocytoma, IDH-wildtype (9400/3)" ], [ "03", "Anaplastic astrocytoma, IDH-mutant (9401/3)" ], [ "04", "Anaplastic astrocytoma, IDH-wildtype (9401/3)" ], [ "05", "Glioblastoma, IDH-wildtype (9440/3)" ], [ "06", "Oligodendroglioma, IDH-mutant and 1 p/19q co-deleted (9450/3)" ], [ "07", "Anaplastic oligodendroglioma, IDH-mutant and 1p/19q co-deleted (9451/3)" ], [ "08", "Medulloblastoma, SHH-activated and TP53-wildtype (9471/3)" ], [ "09", "Embryonal tumor with multilayered rosettes, C19MC-altered (9478/3)" ], [ "85", "Not applicable: Histology not 9400/3, 9401/3, 9440/3, 9450/3, 9451/3, 9471/3, 9478/3" ], [ "86", "Benign or borderline tumor" ], [ "87", "Test ordered, results not in chart" ], [ "88", "Not applicable: Information not collected for this case\n(If this item is required by your standard setter, use of code 88 will result in an edit error.)" ], [ "99", "Not documented in patient record\nNo microscopic confirmation\nBrain molecular markers not assessed or unknown if assessed" ] ]
}