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{
  "id" : "ss2018_esophagus_excluding_gist_57104",
  "algorithm" : "eod_public",
  "version" : "1.1",
  "name" : "SS2018: Esophagus",
  "title" : "Summary Stage 2018: Esophagus",
  "subtitle" : "Summary Stage 2018",
  "notes" : "C150-C155, C158-C159 (8000-8700, 8720-8790, 9700-9701)\n\nC160 and Schema Discriminator 1: EsophagusGEJunction (EGJ)/Stomach: 2 (8000-8149, 8154, 8157, 8160-8231, 8243-8248, 8250-8682, 8690-8700, 8720-8790, 9700-9701)\n\nC150-C155, C158-C160\nC150 Cervical esophagus\nC151 Thoracic esophagus\nC152 Abdominal esophagus\nC153 Upper third of esophagus\nC154 Middle third of esophagus\nC155 Lower third of esophagus\nC158 Overlapping lesion of esophagus\nC159 Esophagus, NOS\nC160 Cardia, esophagogastric junction (EGJ)\n\n**Note 1:** The following sources were used in the development of this chapter\n* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)\n* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/)\n* Collaborative Stage Data Collection System, version 02.05:  https://cancerstaging.org/cstage/Pages/default.aspx \n* Chapter 16 *Esophagus and Esophagogastric Junction*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.\n\n**Note 2:** See the following chapters for the listed histologies \n* C160 (8150-8153, 8155-8156, 8158, 8240-8242, 8249, 8683): *NET Stomach*\n* 8710-8714, 8800-8934, 8940-9137, 9141-9582: *Soft Tissue*\n* 8935-8936: *GIST*\n* 9140: *Kaposi Sarcoma*\n\n**Note 3:** Cancers involving the EGJ that have their epicenter within the proximal 2 cm of the cardia (Siewert types I/II) are to be staged as esophageal cancers (see the Esophagus (excluding GIST) chapter). Cancers whose epicenter is more than 2 cm distal from the EGJ, even if the EGJ is involved, will be staged using the stomach cancer chapter.\n* The Schema Discriminator *EsophagusGEJunction (EGJ)/Stomach* is used to discriminate between EsophagusGEJunction and Stomach which are coded to ICD-O-3 code C160\n\n**Note 4:** Non-invasive carcinomas in the esophagus formerly called in situ are now called high grade dysplasia. High grade dysplasia and severe dysplasia are generally not reportable in cancer registries. \n* Code 0 if your registry collects these tumors",
  "footnotes" : "(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998\n\n(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.\n\n(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)\n\n(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30\n\n(5) Rice, T.W., Kelsen, D., Hofstetter, W.L., et al. **Esophagus and Esophagogastric Junction**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 185-202",
  "last_modified" : "2018-04-19T21:51:25.414Z",
  "definition" : [ {
    "key" : "ss2018",
    "name" : "SS2018",
    "type" : "INPUT"
  }, {
    "key" : "description",
    "name" : "Description",
    "type" : "DESCRIPTION"
  } ],
  "rows" : [ [ "0", "In situ, intraepithelial, non-invasive; high-grade dysplasia  \n- (Adeno)carcinoma, noninvasive, in a polyp" ], [ "1", "Localized only (localized, NOS)\n- Confined to esophagus, NOS\n- Extension through wall, NOS\n- Invasion of \n  + Intramucosa, NOS\n  + Lamina propria\n  + Mucosa, NOS\n  + Muscularis mucosae\n  + Muscularis, NOS\n  + Muscularis propria\n  + Submucosa (superficial invasion)\n- Perimuscular tissue invaded\n- Subserosal tissue/(sub)serosal fat invaded" ], [ "2", "Regional by direct extension only\n- All sites\n  + Adjacent structure(s), NOS\n  + Adventitia and/or soft tissue invaded\n  + Aorta\n  + Azygos vein\n  + Diaphragm (excluding abdominal/lower esophagus, see code 7)\n  + Esophagus is described as \"FIXED\"\n  + Extension to adjacent (connective) tissue WITHOUT perforation of visceral peritoneum covering these structures\n  + Gastric artery\n  + Ligaments\n    * Gastrocolic\n    * Gastrohepatic\n    * Gastrosplenic\n    * Omentum (greater, lesser, NOS)\n  + Mesothelium\n  + Pericardium (excluding thoracic/middle esophagus, see code 7)\n  + Perigastric fat\n  + Peritoneum, NOS\n  + Pleura (excluding cervical/upper esophagus, see code 7)\n  + Serosa (invasion of/or through)\n  + Tunica serosa\n  + Vertebral body\n  + Visceral peritoneum (including perforation)\n- Cervical esophagus\n  + Blood vessel(s)\n     * Carotid artery \n     * Subclavian artery\n  + Carina \n  + Cervical vertebra(e)\n  + Hypopharynx\n  + Jugular vein\n  + Larynx\n  + Thyroid\n  + Trachea \n- Intrathoracic, upper or mid-portion, esophagus\n  + Blood vessel(s), major\n     * Gastric artery/vein\n     * Pulmonary artery/vein \n     * Vena cava \n  + Carina \n  + Stomach, cardia (via serosa)\n  + Trachea \n- Intrathoracic, lower portion (abdominal), esophagus\n  + Blood vessel(s)\n     * Vena cava \n- Intrathoracic esophagus (all portions)\n  + Adjacent rib(s) \n  + Lung via bronchus\n  + Mediastinal structure(s), NOS \n  + Thoracic vertebra(e)\n- Esophagus GE Junction\n  + Liver\n  + Pancreas\n  + Small intestine (duodenum [via serosa], ileum, jejunum)\n  + Spleen\n  + Transverse colon (including flexures)" ], [ "3", "Regional lymph node(s) involved only\n- All subsites \n  + Nodule(s) in perigastric fat\n  + Peri-/paraesophageal (8L, 8M) (excluding GE junction)\n  + Regional lymph node(s), NOS\n    * Lymph node(s), NOS\n- Cervical esophagus only\n  + Cervical, NOS\n     * Anterior deep cervical (laterotracheal) (recurrent laryngeal)\n     * Deep cervical, NOS\n     * Internal jugular, NOS\n        - Jugulodigastric (subdigastric)\n        - Upper, NOS\n  + Scalene (inferior deep cervical) (1)\n  + Supraclavicular (transverse cervical) (1)\n- Intrathoracic esophagus, upper or middle, only\n  + Internal jugular, NOS\n     * Deep cervical, NOS\n         - Jugulodigastric (subdigastric)\n         - Jugulo-omohyoid (supraomohyoid)\n         - Lower, NOS\n         - Middle\n         - Upper cervical, NOS\n  + Intrabronchial\n    * Carinal (tracheobronchial) (10R, 10L) (tracheal bifurcation)\n    * Hilar (bronchopulmonary) (proximal lobar) (pulmonary root)\n    * Left gastric (superior gastric) (17)\n       - Cardiac (cardial)\n       - Lesser curvature\n       - Perigastric, NOS\n    * Peritracheal\n   + Posterior mediastinal (tracheoesophageal)\n   + Superior mediastinal\n- Intrathoracic esophagus, lower (abdominal) only\n  + Left gastric (superior gastric) (17)\n    * Cardiac (cardial)\n    * Lesser curvature\n    * Perigastric, NOS\n  + Posterior mediastinal (3P) (tracheoesophageal)\n- Esophagus GE Junction\n  + Celiac (20)\n  + Hepatic (excluding gastrohepatic and hepatoduodenal)\n  + Left gastric (superior gastric), NOS\n    * Cardiac\n    * Cardioesophageal\n    * Gastric, left (17)\n    * Gastropancreatic, left\n    * Lesser curvature\n    * Lesser omental\n    * Pericardial (16)\n + Pancreaticosplenic (pancreaticolineal)\n + Pancreatoduodenal\n + Perigastric, NOS  \n + Peripancreatic \n + Right gastric (inferior gastric), NOS\n    * Gastrocolic\n    * Gastroduodenal\n    * Gastroepiploic (gastro-omental), right or NOS\n    * Gastrohepatic\n    * Greater curvature\n    * Greater omental\n    * Pyloric, NOS\n       - Infrapyloric (subpyloric)\n       - Suprapyloric\n  + Splenic (lienal), NOS\n    * Gastroepiploic (gastro-omental), left\n    * Splenic hilar" ], [ "4", "Regional by BOTH direct extension AND regional lymph node(s) involved\n- Codes (2) + (3)" ], [ "7", "Distant site(s)/lymph node(s) involved\n- Distant site(s) (including further contiguous extension)\n  + All subsites\n     * Airway\n     * Stated as unresectable, NOS\n     * Vertebral body\n  + Abdomen/lower esophagus\n     * Diaphragm fixed\n  + Cervical/upper esophagus\n     * Lung\n     * Pleura\n     * Mainstem bronchus\n  + Thoracic/middle esophagus\n     * Pericardium \n  + Esophagus GE Junction\n     * Abdominal wall\n     * Adrenal (suprarenal) gland\n     * Kidney\n     * Pulmonary ligament (9)\n     * Retroperitoneum\n     * Trachea\n- Distant lymph node(s), NOS\n  + All subsites\n     * Anterior mediastinal (6)\n     * Common hepatic (18)\n     * Diaphragmatic (15)\n     * Mediastinal, NOS\n     * Splenic (19)\n     * Subcarinal (tracheal carina) (7)\n   + Cervical esophagus\n     * Aortopulmonary (5)\n     * Para-aortic (ascending aorta or phrenic)\n        - Subaortic\n     * Paratracheal (2R, 2L, 4R, 4L)\n     * Posterior mediastinal (3P)\n     * Superior mediastinal\n   + Intrathoracic esophagus, upper or middle, only\n     * Aortopulmonary (5)\n        - Para-aortic (ascending aorta or phrenic)\n     * Cervical\n   + Lower thoracic (abdominal) esophagus\n      * Aortopulmonary (5)\n         - Para-aortic (ascending aorta or phrenic)\n         - Subaortic \n      * Celiac (20)\n     * Paratracheal (2R, 2L, 4R, 4L)\n     * Superior mediastinal\n   + Esophagus GE Junction\n      * Hepatoduodenal\n      * Mesenteric, NOS\n          - Inferior mesenteric\n          - Superior mesenteric\n      * Para-aortic\n      * Paraesophageal, NOS\n      * Periesophageal, NOS\n         - Anterior mediastinal (6)\n         - Aortopulmonary (5)\n         - Paraesophageal, lower (8l)\n         - Paraesophageal, middle (8m)\n         - Paratracheal, lower (4L, 4R)\n         - Paratracheal, upper (2L, 2R)\n         - Posterior mediastinal (3p)\n         - Supraclavicular (1)\n         - Tracheobronchial (hilar) (10L, 10R)\n      * Porta hepatis (portal) (hilar) (in hilus of liver)\n      * Retropancreatic\n      * Retroperitoneal\n- Distant metastasis, NOS\n   + Carcinomatosis\n   + Distant metastasis WITH or WITHOUT distant lymph node(s)" ], [ "9", "Unknown if extension or metastasis" ] ]
}




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