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{
  "id" : "ss2018_lymphoma_27031",
  "algorithm" : "eod_public",
  "version" : "1.1",
  "name" : "SS2018: Lymphoma",
  "title" : "Summary Stage 2018: Lymphoma",
  "subtitle" : "Summary Stage 2018",
  "notes" : "**Lymphoma**\n\n9590, 9596-9663, 9673-9699, 9702-9719, 9725-9726, 9735, 9737-9738, 9823, 9826-9827 (varying primary sites and histologies)\n* *See Summary Stage 2018 Manual, Appendix III for a detailed listing of primary site/histology combinations for this schema*\n\n9591 and Schema Discriminator 1: 3, 9 (C000-C440, C442-C689, C691-C694, C698-C809)\n\n**Note 1:** The following sources were used in the development of this chapter\n* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)\n* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/)\n* Collaborative Stage Data Collection System, version 02.05:  https://cancerstaging.org/cstage/Pages/default.aspx \n* Chapter 79 *Hodgkin and Non-Hodgkin Lymphomas*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.\n* Chapter 80 *Pediatric Hodgkin and Non-Hodgkin Lymphomas*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.\n\n**Note 2:** See the following schemas for the listed histologies\n* C441, C690, C695-C696 (9590-9699, 9702-9719, 9725-9726, 9735, 9737-9738, 9823, 9826-9827): *Lymphoma Ocular Adnexa*\n* C440, C442-C449, C510, C609, C632 (9597, 9680, 9708-9709, 9712, 9718-9719, 9726): *Primary Cutaneous Lymphomas*\n* C700, C710-C719 (9680, 9699, 9700-9714): *Brain*\n* C701, C709, C720-C725, C728-C729 (9680, 9699, 9700-9714): *CNS Other*\n* C751-C753 (9680, 9699, 9700-9714): *Intracranial Gland*\n* 9591 and Schema Discriminator 1: 1, 2 (C000-C440, C442-C689, C691-C694, C698-C809): *HemeRetic*\n\n\n**Note 3:** Chapter includes the preferred terms based on the *2017 WHO Classification of Haematopoietic and Lymphoid Tissues*\n\n9590 Malignant lymphoma, NOS\n9591 Non-Hodgkin lymphoma, NOS\n9596 B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and classic Hodgkin lymphoma\n9597 Primary cutaneous follicle centre lymphoma\n9650 Classical Hodgkin lymphoma\n9651 Lymphocyte-rich classic Hodgkin lymphoma\n9652 Mixed cellularity classic Hodgkin lymphoma\n9653 Lymphocyte-depleted classic Hodgkin lymphoma \n9659 Nodular lymphocyte predominant Hodgkin lymphoma\n9663 Nodular sclerosis classic Hodgkin lymphoma \n9673 Mantle cell lymphoma\n9678 Primary effusion lymphoma \n9679 Primary mediastinal (thymic) large B-cell lymphoma\n9680 Diffuse large B-cell lymphoma (DLBCL)\n9687 Burkitt lymphoma\n9688 T-cell/histiocyte-rich large B-cell lymphoma\n9689 Splenic marginal zone lymphoma\n9690 Follicular lymphoma\n9691 Follicular lymphoma, grade 2\n9695 Follicular lymphoma, grade 1\n9698 Follicular lymphoma, grade 3\n9699 Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)\n9702 Peripheral T-cell lymphoma, NOS\n9705 Angioimmunoblastic T-cell lymphoma\n9708 Subcutaneous panniculitis-like T-cell lymphoma\n9709 Primary cutaneous peripheral T-cell lymphomas\n9712 Intravascular large B-cell lymphoma\n9714 Anaplastic large cell lymphoma, ALK-positive\n9716 Hepatosplenic T-cell lymphoma\n9717 Enteropathy-associated T-cell lymphoma\n9718 Primary cutaneous anaplastic large cell lymphoma\n9719 Extranodal NK/T-cell lymphoma, nasal type\n9725 Hydroa vacciniforme-like lymphoma\n9726 Primary cutaneous gamma-delta T-cell lymphoma\n9735 Plasmablastic lymphoma\n9737 ALK-positive large B-cell lymphoma\n9738 HHV8-positive DLBCL, NOS\n9823 Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma\n9826 Burkitt cell leukemia\n9827 Adult T-cell leukemia/lymphoma",
  "footnotes" : "(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998\n\n(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.\n\n(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)\n\n(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30\n\n(5) **Introduction to Hematologic Malignancies**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 931-935\n\n(6) Zelenetz, A.D., Jaffe, E.S., Leonard, J.P., et al. **Hodgkin and Non-Hodgkin Lymphomas**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 937-958\n\n(7) Link, M.P., Jaffe, E.S., Leonard, J.P. **Pediatric Hodgkin and Non-Hodgkin Lymphomas**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 959-965",
  "last_modified" : "2018-04-19T21:51:26.716Z",
  "definition" : [ {
    "key" : "ss2018",
    "name" : "SS2018",
    "type" : "INPUT"
  }, {
    "key" : "description",
    "name" : "Description",
    "type" : "DESCRIPTION"
  } ],
  "rows" : [ [ "1", "Localized only\n- Involvement of multiple nodal chains in the SAME lymph node region\n- Multifocal involvement of one extralymphatic organ/site (except lung/liver) WITHOUT nodal involvement\n- Single extralymphatic site WITHOUT nodal involvement\n- Single lymph node region involved" ], [ "2", "Regional, NOS\n- Bulky disease present\n- Contiguous extension between extralymphatic sites and regional nodes \n  + WITH or WITHOUT involvement of other nodal regions on SAME side of diaphragm\n- Localized involvement of a single extralymphatic organ/site \n  + WITH involvement of its regional lymph node(s) OR\n  + WITH involvement of other lymph node(s) on the SAME side of the diaphragm\n- Two or more lymph node regions involved SAME side of diaphragm" ], [ "7", "Distant site(s)/lymph node(s) involved\n- Distant involvement\n  + Diffuse or disseminated (multifocal) involvement of ONE extralymphatic organ/site \n     * WITH associated lymph node involvement OR\n  + Diffuse or disseminated (multifocal) involvement of ONE or MORE extralymphatic organ(s)/site(s) \n     * WITH or WITHOUT associated lymph node involvement\n  + Involvement of isolated extralymphatic organ in absence of involvement of adjacent lymph nodes, but in conjunction with disease in distant sites\n  + Involvement of lymph node regions on BOTH sides of the diaphragm\n     * OR nodes ABOVE the diaphragm involved WITH spleen involvement \n  + Multifocal involvement of one extralymphatic organ/site WITH nodal involvement\n  + Noncontiguous extralymphatic organ involvement in conjunction with nodal disease (two or more sites involved)\n- Distant metastasis, NOS\n  + Bone marrow\n  + Cerebrospinal fluid (CSF)\n  + Liver\n  + Lung (other than by direct extension in code 2)" ], [ "9", "Unknown if extension or metastasis" ] ]
}




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