topics-and-qrels.topics.covid-round2.xml Maven / Gradle / Ivy

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    coronavirus origin
    what is the origin of COVID-19
    seeking range of information about the SARS-CoV-2 virus's origin, including its evolution, animal source, and first transmission into humans
  
  
    coronavirus response to weather changes
    how does the coronavirus respond to changes in the weather
    seeking range of information about the SARS-CoV-2 virus viability in different weather/climate conditions as well as information related to transmission of the virus in different climate conditions
  
  
    coronavirus immunity
    will SARS-CoV2 infected people develop immunity? Is cross protection possible?
    seeking studies of immunity developed due to infection with SARS-CoV2 or cross protection gained due to infection with other coronavirus types
  
  
    how do people die from the coronavirus
    what causes death from Covid-19?
    Studies looking at mechanisms of death from Covid-19.
  
  
    animal models of COVID-19
    what drugs have been active against SARS-CoV or SARS-CoV-2 in animal studies?
    Papers that describe the results  of testing drugs that bind to spike proteins of the virus or any other drugs in any animal models. Papers about SARS-CoV-2 infection in cell culture assays are also relevant.
  
  
    coronavirus test rapid testing
    what types of rapid testing for Covid-19 have been developed?
    Looking for studies identifying ways to diagnose Covid-19 more rapidly.
  
  
    serological tests for coronavirus
    are there serological tests that detect antibodies to coronavirus?
    Looking for assays that measure immune response to COVID-19 that will help determine past infection and subsequent possible immunity.
  
  
    coronavirus under reporting
    how has lack of testing availability led to underreporting of true incidence of Covid-19?
    Looking for studies answering questions of impact of lack of complete testing for Covid-19 on incidence and prevalence of Covid-19.
  
  
    coronavirus in Canada
    how has COVID-19 affected Canada
    seeking data related to infections (confirm, suspected, and projected) and health outcomes (symptoms, hospitalization, intensive care, mortality)
  
  
    coronavirus social distancing impact
    has social distancing had an impact on slowing the spread of COVID-19?
    seeking specific information on studies that have measured COVID-19's transmission in one or more social distancing (or non-social distancing) approaches
  
  
    coronavirus hospital rationing
    what are the guidelines for triaging patients infected with coronavirus?
    Seeking information on any guidelines for prioritizing COVID-19 patients infected with coronavirus based on demographics, clinical signs, serology and other tests.
  
  
    coronavirus quarantine
    what are best practices in hospitals and at home in maintaining quarantine?
    Seeking information on best practices for activities and duration of quarantine for those exposed and/ infected to COVID-19 virus.
  
  
    how does coronavirus spread
    what are the transmission routes of coronavirus?
    Looking for information on all possible ways to contract COVID-19 from people, animals and objects
  
  
    coronavirus super spreaders
    what evidence is there related to COVID-19 super spreaders
    seeking range of information related to the number and proportion of super spreaders, their patterns of behavior that lead to spread, and potential prevention strategies targeted specifically toward super spreaders
  
  
    coronavirus outside body
    how long can the coronavirus live outside the body
    seeking range of information on the SARS-CoV-2's virus's survival in different environments (surfaces, liquids, etc.) outside the human body while still being viable for transmission to another human
  
  
    how long does coronavirus survive on surfaces
    how long does coronavirus remain stable  on surfaces?
    Studies of time SARS-CoV-2 remains stable after being deposited from an infected person on everyday surfaces in a household or hospital setting, such as through coughing or touching objects.
  
  
    coronavirus clinical trials
    are there any clinical trials available for the coronavirus
    seeking specific COVID-19 clinical trials ranging from trials in recruitment to completed trials with results
  
  
    masks prevent coronavirus
    what are the best masks for preventing infection by Covid-19?
    What types of masks should or should not be used to prevent infection by Covid-19?
  
  
    what alcohol sanitizer kills coronavirus
    what type of hand sanitizer is needed to destroy Covid-19?
    Studies assessing chemicals and their concentrations needed to destroy the Covid-19 virus.
  
  
    coronavirus and ACE inhibitors
    are patients taking Angiotensin-converting enzyme inhibitors (ACE) at increased risk for COVID-19?
    Looking for information on interactions between  coronavirus and  angiotensin converting enzyme 2 (ACE2) receptors, risk for patients taking these medications, and recommendations for these patients.
  
  
    coronavirus mortality
    what are the mortality rates overall and in specific populations
    Seeking  information on COVID-19 fatality rates in different countries and in different population groups based on gender, blood types, or other factors
  
  
    coronavirus heart impacts
    are cardiac complications likely in patients with COVID-19?
    Seeking information on the types, frequency and mechanisms of cardiac complications caused by coronavirus.
  
  
    coronavirus hypertension
    what kinds of complications related to COVID-19 are associated with hypertension?
    seeking specific outcomes that hypertensive  (any type) patients are more/less likely to face if infected with the virus
  
  
    coronavirus diabetes
    what kinds of complications related to COVID-19 are associated with diabetes
    seeking specific outcomes that diabetic (any type) patients are more/less likely to face if infected with the virus
  
  
    coronavirus biomarkers
    which biomarkers predict the severe clinical course of 2019-nCOV infection?
    Looking for information on biomarkers that predict disease outcomes in people infected with coronavirus, specifically those that predict severe and fatal outcomes.
  
  
    coronavirus early symptoms
    what are the initial symptoms of Covid-19?
    Studies of patients and the first clinical manifestations they develop upon active infection?
  
  
    coronavirus asymptomatic
    what is known about those infected with Covid-19 but are asymptomatic?
    Studies of people who are known to be infected with Covid-19 but show no symptoms?
  
  
    coronavirus hydroxychloroquine
    what evidence is there for the value of hydroxychloroquine in treating Covid-19?
    Basic science or clinical studies assessing the benefit and harms of treating Covid-19 with hydroxychloroquine.
  
  
    coronavirus drug repurposing
    which SARS-CoV-2 proteins-human proteins interactions indicate potential for drug targets. Are there approved drugs that can be repurposed based on this information?
    Seeking information about protein-protein interactions for any of the SARS-CoV-2  structural proteins that represent a promising therapeutic target,  and the drug  molecules that may inhibit the virus and the host cell receptors at entry step.
  
  
    coronavirus remdesivir
    is remdesivir an effective treatment for COVID-19
    seeking specific information on clinical outcomes in COVID-19 patients treated with remdesivir
  
  
    difference between coronavirus and flu
    How does the coronavirus differ from seasonal flu?
    Includes studies ranging from those focusing on genomic differences to global public health impacts, but must draw direct comparisons between COVID-19 and seasonal influenza.
  
  
    coronavirus subtypes
    Does SARS-CoV-2 have any subtypes, and if so what are they?
    Papers that discuss subtypes of the virus, from named subtypes to speculative subtypes based on genomic or geographic clustering.
  
  
    coronavirus vaccine candidates
    What vaccine candidates are being tested for Covid-19?
    Seeking studies that discuss possible, but specific, COVID-19 vaccines. Includes articles from those describing the mechanisms of action of specific proposed vaccines to actual clinical trials, but excluding articles that do not name a specific vaccine candidate.
  
  
    coronavirus recovery
    What are the longer-term complications of those who recover from COVID-19?
    Seeking information on the health outcomes for those that recover from the virus. Excludes studies only focusing on adverse effects related to a particular COVID-19 drug.
  
  
    coronavirus public datasets
    What new public datasets are available related to COVID-19?
    Seeking articles that specifically release new data related to SARS-CoV-2 or COVID-19, including genomic data, patient data, public health data, etc. Articles that reference previously existing datasets are not relevant.