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org.obolibrary.oboformat.parser.XrefExpander Maven / Gradle / Ivy

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package org.obolibrary.oboformat.parser;

import java.util.Collection;
import java.util.HashMap;
import java.util.Map;

import javax.annotation.Nonnull;

import org.obolibrary.oboformat.model.Clause;
import org.obolibrary.oboformat.model.Frame;
import org.obolibrary.oboformat.model.Frame.FrameType;
import org.obolibrary.oboformat.model.FrameMergeException;
import org.obolibrary.oboformat.model.OBODoc;
import org.obolibrary.oboformat.model.Xref;
import org.obolibrary.oboformat.parser.OBOFormatConstants.OboFormatTag;
import org.slf4j.Logger;
import org.slf4j.LoggerFactory;

/** xref expander */
public class XrefExpander {

    protected static final Logger LOG = LoggerFactory.getLogger(XrefExpander.class);
    OBODoc sourceOBODoc;
    OBODoc targetOBODoc;
    String targetBase;
    @Nonnull
    Map treatMap = new HashMap<>();
    @Nonnull
    Map targetDocMap = new HashMap<>();

    /**
     * @param src
     *        src
     * @throws InvalidXrefMapException
     *         InvalidXrefMapException
     */
    public XrefExpander(@Nonnull OBODoc src) {
        sourceOBODoc = src;
        Frame shf = src.getHeaderFrame();
        String ontId = shf.getTagValue(OboFormatTag.TAG_ONTOLOGY, String.class);
        String tgtOntId = ontId + "/xref_expansions";
        targetOBODoc = new OBODoc();
        Frame thf = new Frame(FrameType.HEADER);
        thf.addClause(new Clause(OboFormatTag.TAG_ONTOLOGY, tgtOntId));
        targetOBODoc.setHeaderFrame(thf);
        sourceOBODoc.addImportedOBODoc(targetOBODoc);
        setUp();
    }

    /**
     * @param src
     *        src
     * @param targetBase
     *        targetBase
     * @throws InvalidXrefMapException
     *         InvalidXrefMapException
     */
    public XrefExpander(OBODoc src, String targetBase) {
        sourceOBODoc = src;
        this.targetBase = targetBase;
        setUp();
    }

    /**
     * @param src
     *        src
     * @param tgt
     *        tgt
     * @throws InvalidXrefMapException
     *         InvalidXrefMapException
     */
    public XrefExpander(OBODoc src, OBODoc tgt) {
        sourceOBODoc = src;
        targetOBODoc = tgt;
        setUp();
    }

    /**
     * @throws InvalidXrefMapException
     *         InvalidXrefMapException
     */
    public final void setUp() {
        // required for translation of IDs
        // obo2owl = new Obo2Owl();
        // obo2owl.setObodoc(sourceOBODoc);
        Map relationsUseByIdSpace = new HashMap<>();
        for (Clause c : sourceOBODoc.getHeaderFrame().getClauses()) {
            String[] parts;
            String v = c.getValue(String.class);
            if (v == null) {
                LOG.error("problem with header clause in xref expansion: {}", c);
                continue;
            }
            parts = v.split("\\s");
            String relation = null;
            String idSpace = parts[0];
            if (c.getTag().equals(OboFormatTag.TAG_TREAT_XREFS_AS_EQUIVALENT.getTag())) {
                addRule(parts[0], new EquivalenceExpansion());
                // addMacro(idSpace,"is_specific_equivalent_of","Class: ?X
                // EquivalentTo: ?Y and "+oboIdToIRI(parts[1])+" some
                // "+oboIdToIRI(parts[2]));
            } else if (c.getTag().equals(OboFormatTag.TAG_TREAT_XREFS_AS_GENUS_DIFFERENTIA.getTag())) {
                addRule(idSpace, new GenusDifferentiaExpansion(parts[1], parts[2]));
                // addMacro(idSpace,"is_generic_equivalent_of","Class: ?Y
                // EquivalentTo: ?X and "+oboIdToIRI(parts[1])+" some
                // "+oboIdToIRI(parts[2]));
                relationsUseByIdSpace.put(idSpace, parts[1]);
                relation = parts[1];
            } else if (c.getTag().equals(OboFormatTag.TAG_TREAT_XREFS_AS_REVERSE_GENUS_DIFFERENTIA.getTag())) {
                addRule(idSpace, new ReverseGenusDifferentiaExpansion(parts[1], parts[2]));
                // addMacro(idSpace,"is_generic_equivalent_of","Class: ?Y
                // EquivalentTo: ?X and "+oboIdToIRI(parts[1])+" some
                // "+oboIdToIRI(parts[2]));
                relationsUseByIdSpace.put(idSpace, parts[1]);
                relation = parts[1];
            } else if (c.getTag().equals(OboFormatTag.TAG_TREAT_XREFS_AS_HAS_SUBCLASS.getTag())) {
                addRule(idSpace, new HasSubClassExpansion());
            } else if (c.getTag().equals(OboFormatTag.TAG_TREAT_XREFS_AS_IS_A.getTag())) {
                addRule(idSpace, new IsaExpansion());
            } else if (c.getTag().equals(OboFormatTag.TAG_TREAT_XREFS_AS_RELATIONSHIP.getTag())) {
                addRule(idSpace, new RelationshipExpansion(parts[1]));
                relationsUseByIdSpace.put(idSpace, parts[1]);
                relation = parts[1];
            } else {
                continue;
            }
            if (targetBase != null) {
                // create a new bridge ontology for every expansion macro
                OBODoc tgt = new OBODoc();
                Frame thf = new Frame(FrameType.HEADER);
                thf.addClause(new Clause(OboFormatTag.TAG_ONTOLOGY, targetBase + "-" + idSpace.toLowerCase()));
                tgt.setHeaderFrame(thf);
                targetDocMap.put(idSpace, tgt);
                sourceOBODoc.addImportedOBODoc(tgt);
                if (relation != null) {
                    // See 4.4.2
                    // "In addition, any Typedef frames for relations used in a
                    // header macro
                    // are also copied into the corresponding bridge ontology
                    Frame tdf = sourceOBODoc.getTypedefFrame(relation);
                    if (tdf != null) {
                        try {
                            tgt.addTypedefFrame(tdf);
                        } catch (FrameMergeException e) {
                            LOG.debug("frame merge failed", e);
                        }
                    }
                }
            }
        }
    }

    /**
     * @param idSpace
     *        idSpace
     * @return target doc
     */
    public OBODoc getTargetDoc(String idSpace) {
        if (targetOBODoc != null) {
            return targetOBODoc;
        }
        return targetDocMap.get(idSpace);
    }

    private void addRule(String db, @Nonnull Rule rule) {
        if (treatMap.containsKey(db)) {
            throw new InvalidXrefMapException(db);
        }
        rule.idSpace = db;
        treatMap.put(db, rule);
    }

    /** expand xrefs */
    public void expandXrefs() {
        for (Frame f : sourceOBODoc.getTermFrames()) {
            String id = f.getTagValue(OboFormatTag.TAG_ID, String.class);
            Collection clauses = f.getClauses(OboFormatTag.TAG_XREF);
            for (Clause c : clauses) {
                Xref x = c.getValue(Xref.class);
                if (x != null) {
                    String xid = x.getIdref();
                    String s = getIDSpace(xid);
                    if (treatMap.containsKey(s)) {
                        treatMap.get(s).expand(f, id, xid);
                    }
                }
            }
        }
    }

    private static String getIDSpace(@Nonnull String x) {
        String[] parts = x.split(":", 2);
        return parts[0];
    }

    /** rule */
    public abstract class Rule {

        protected String xref;
        /** id space */
        public String idSpace;

        /**
         * @param sf
         *        sf
         * @param id
         *        id
         * @param xRef
         *        xref
         */
        public abstract void expand(@Nonnull Frame sf, String id, String xRef);

        @Nonnull
        protected Frame getTargetFrame(String id) {
            Frame f = getTargetDoc(idSpace).getTermFrame(id);
            if (f == null) {
                f = new Frame();
                f.setId(id);
                try {
                    getTargetDoc(idSpace).addTermFrame(f);
                } catch (FrameMergeException e) {
                    // this should be impossible
                    LOG.error("Frame merge exceptions should not be possible", e);
                }
            }
            return f;
        }
    }

    /** equivalence expansion */
    public class EquivalenceExpansion extends Rule {

        @Override
        public void expand(@Nonnull Frame sf, String id, String xRef) {
            Clause c = new Clause(OboFormatTag.TAG_EQUIVALENT_TO, xRef);
            sf.addClause(c);
        }
    }

    /** subclass expansion */
    public class HasSubClassExpansion extends Rule {

        @Override
        public void expand(Frame sf, String id, String xRef) {
            Clause c = new Clause(OboFormatTag.TAG_IS_A, id);
            getTargetFrame(xRef).addClause(c);
        }
    }

    /** genus diff expansion */
    public class GenusDifferentiaExpansion extends Rule {

        protected final String rel;
        protected final String tgt;

        /**
         * @param rel
         *        rel
         * @param tgt
         *        tgt
         */
        public GenusDifferentiaExpansion(String rel, String tgt) {
            this.rel = rel;
            this.tgt = tgt;
        }

        @Override
        public void expand(Frame sf, String id, String xRef) {
            Clause gc = new Clause(OboFormatTag.TAG_INTERSECTION_OF, xRef);
            Clause dc = new Clause(OboFormatTag.TAG_INTERSECTION_OF);
            dc.setValue(rel);
            dc.addValue(tgt);
            getTargetFrame(id).addClause(gc);
            getTargetFrame(id).addClause(dc);
        }
    }

    /** reverse genus differentia expansion */
    public class ReverseGenusDifferentiaExpansion extends Rule {

        protected final String rel;
        protected final String tgt;

        /**
         * @param rel
         *        rel
         * @param tgt
         *        tgt
         */
        public ReverseGenusDifferentiaExpansion(String rel, String tgt) {
            this.rel = rel;
            this.tgt = tgt;
        }

        @Override
        public void expand(Frame sf, String id, String xRef) {
            Clause gc = new Clause(OboFormatTag.TAG_INTERSECTION_OF, id);
            Clause dc = new Clause(OboFormatTag.TAG_INTERSECTION_OF);
            dc.setValue(rel);
            dc.addValue(tgt);
            getTargetFrame(xRef).addClause(gc);
            getTargetFrame(xRef).addClause(dc);
        }
    }

    /** is a expansion */
    public class IsaExpansion extends Rule {

        @Override
        public void expand(Frame sf, String id, String xRef) {
            Clause c = new Clause(OboFormatTag.TAG_IS_A, xRef);
            getTargetFrame(id).addClause(c);
        }
    }

    /** relationship expansion */
    public class RelationshipExpansion extends Rule {

        protected final String rel;

        /**
         * @param rel
         *        rel
         */
        public RelationshipExpansion(String rel) {
            this.rel = rel;
        }

        @Override
        public void expand(Frame sf, String id, String xRef) {
            Clause c = new Clause(OboFormatTag.TAG_RELATIONSHIP, rel);
            c.addValue(xRef);
            getTargetFrame(id).addClause(c);
        }
    }
}




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