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/*******************************************************************************
 * Copyright (c) 2010 Haifeng Li
 *   
 * Licensed under the Apache License, Version 2.0 (the "License");
 * you may not use this file except in compliance with the License.
 * You may obtain a copy of the License at
 *  
 *     http://www.apache.org/licenses/LICENSE-2.0
 *
 * Unless required by applicable law or agreed to in writing, software
 * distributed under the License is distributed on an "AS IS" BASIS,
 * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 * See the License for the specific language governing permissions and
 * limitations under the License.
 *******************************************************************************/
package smile.data.parser.microarray;

import java.io.BufferedReader;
import java.io.File;
import java.io.FileInputStream;
import java.io.FileNotFoundException;
import java.io.IOException;
import java.io.InputStream;
import java.io.InputStreamReader;
import java.net.URI;
import java.text.ParseException;
import smile.data.Attribute;
import smile.data.AttributeDataset;
import smile.data.Datum;
import smile.data.NumericAttribute;

/**
 * ExpRESsion (with P and A calls) file parse. The RES file format
 * is a tab delimited file format that describes a gene expression dataset.
 * The main difference between RES and GCT file formats is the RES file format
 * contains labels for each gene's absent (A) versus present (P) calls as
 * generated by Affymetrix's GeneChip software.
 * 

* The first line contains a list of labels identifying the samples associated * with each of the columns in the remainder of the file. Two tabs (\t\t) * separate the sample identifier labels because each sample contains two data * values (an expression value and a present/marginal/absent call). *

* Line format: *

* Description (tab) Accession (tab) (sample 1 name) (tab) (tab) (sample 2 name) (tab) (tab) ... (sample N name) *

* For example: *

* Description Accession DLBC1_1 DLBC2_1 ... DLBC58_0 *

* The second line contains a list of sample descriptions. *

* Line format: *

* (tab) (sample 1 description) (tab) (tab) (sample 2 description) (tab) (tab) ... (sample N description) *

* Example: *

* MG2000062219AA MG2000062256AA/scale factor=1.2172 ... MG2000062211AA/scale factor=1.1214 *

* The third line contains a number indicating the number of rows in the data * table that is contained in the remainder of the file. *

* Line format: *

* (# of data rows) *

* For example: *

* 7129 *

* The remainder of the data file contains data for each of the genes. There * is one row for each gene and two columns for each of the samples. The first * two fields in the row contain the description and name for each of the genes * (names and descriptions can contain spaces since fields are separated by * tabs). The description field is optional but the tab following it is not. * Each sample has two pieces of data associated with it: an expression value * and an associated Absent/Marginal/Present (A/M/P) call. The A/M/P calls are * generated by microarray scanning software (such as Affymetrix's GeneChip * software) and are an indication of the confidence in the measured expression * value. *

* Line format: *

* (gene description) (tab) (gene name) (tab) (sample 1 data) (tab) (sample 1 A/P call) (tab) (sample 2 data) (tab) (sample 2 A/P call) (tab) ... (sample N data) (tab) (sample N A/P call) *

* For example: *

* AFFX-BioB-5_at (endogenous control) AFFX-BioB-5_at -104 A -152 A ... -44 A *

* * @author Haifeng Li */ public class RESParser { /** * Constructor. */ public RESParser() { } /** * Parse a RES dataset from given URI. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(URI uri) throws FileNotFoundException, IOException, ParseException { return parse(new File(uri)); } /** * Parse a RES dataset from given URI. * @param uri the URI of data source. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(String name, URI uri) throws FileNotFoundException, IOException, ParseException { return parse(name, new File(uri)); } /** * Parse a RES dataset from given file. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(String path) throws FileNotFoundException, IOException, ParseException { return parse(new File(path)); } /** * Parse a RES dataset from given file. * @param path the file path of data source. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(String name, String path) throws FileNotFoundException, IOException, ParseException { return parse(name, new File(path)); } /** * Parse a RES dataset from given file. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(File file) throws FileNotFoundException, IOException, ParseException { return parse(file.getPath(), new FileInputStream(file)); } /** * Parse a RES dataset from given file. * @param file the file of data source. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(String name, File file) throws FileNotFoundException, IOException, ParseException { return parse(name, new FileInputStream(file)); } /** * Parse a RES dataset from an input stream. * @param name the name of dataset. * @param stream the input stream of data. * @throws java.io.FileNotFoundException */ public AttributeDataset parse(String name, InputStream stream) throws IOException, ParseException { BufferedReader reader = new BufferedReader(new InputStreamReader(stream)); String line = reader.readLine(); if (line == null) { throw new IOException("Empty data source."); } String[] tokens = line.split("\t", -1); int p = (tokens.length - 2) / 2; line = reader.readLine(); if (line == null) { throw new IOException("Premature end of file."); } String[] samples = line.split("\t", -1); if (samples.length != tokens.length-1) { throw new IOException("Invalid sample description header."); } Attribute[] attributes = new Attribute[p]; for (int i = 0; i < p; i++) { attributes[i] = new NumericAttribute(tokens[2*i+2], samples[2*i+1]); } line = reader.readLine(); if (line == null) { throw new IOException("Premature end of file."); } int n = Integer.valueOf(line); if (n <= 0) { throw new IOException("Invalid number of rows: " + n); } AttributeDataset data = new AttributeDataset(name, attributes); for (int i = 0; i < n; i++) { line = reader.readLine(); if (line == null) { throw new IOException("Premature end of file."); } tokens = line.split("\t", -1); if (tokens.length != samples.length+1) { throw new IOException(String.format("Invalid number of elements of line %d: %d", i+4, tokens.length)); } double[] x = new double[p]; for (int j = 0; j < p; j++) { x[j] = Double.valueOf(tokens[2*j+2]); } Datum datum = new Datum(x); datum.name = tokens[1]; datum.description = tokens[0]; data.add(datum); } reader.close(); return data; } }




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