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Next generation sequencing (NGS/HTS) reads.
/*
ngs-reads Next generation sequencing (NGS/HTS) reads.
Copyright (c) 2014 National Marrow Donor Program (NMDP)
This library is free software; you can redistribute it and/or modify it
under the terms of the GNU Lesser General Public License as published
by the Free Software Foundation; either version 3 of the License, or (at
your option) any later version.
This library is distributed in the hope that it will be useful, but WITHOUT
ANY WARRANTY; with out even the implied warranty of MERCHANTABILITY or
FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public
License for more details.
You should have received a copy of the GNU Lesser General Public License
along with this library; if not, write to the Free Software Foundation,
Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA.
> http://www.gnu.org/licenses/lgpl.html
*/
package org.nmdp.ngs.reads.coverage;
import static com.google.common.base.Preconditions.checkArgument;
import org.biojava.bio.seq.Sequence;
import org.biojava.bio.symbol.IntegerAlphabet;
import org.biojava.bio.symbol.SymbolList;
/**
* Minimum coverage strategy.
*/
public final class MinimumCoverageStrategy extends AbstractCoverageStrategy {
/** Minimum coverage. */
private final int minimumCoverage;
/**
* Create a new minimum coverage strategy with the specified minimum coverage.
*
* @param minimumCoverage minimum coverage, must be at least 0
*/
public MinimumCoverageStrategy(final int minimumCoverage) {
checkArgument(minimumCoverage > 0, "minimumCoverage must be at least 0");
this.minimumCoverage = minimumCoverage;
}
@Override
protected boolean evaluate(final Sequence reference, final SymbolList coverage) {
int min = Integer.MAX_VALUE;
for (int i = 1, size = coverage.length() + 1; i < size; i++) {
int c = ((IntegerAlphabet.IntegerSymbol) coverage.symbolAt(i)).intValue();
if (c < min) {
min = c;
}
}
return min >= minimumCoverage;
}
}