org.opencb.cellbase.lib.builders.RegulatoryFeatureBuilder Maven / Gradle / Ivy
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/*
* Copyright 2015-2020 OpenCB
*
* Licensed under the Apache License, Version 2.0 (the "License");
* you may not use this file except in compliance with the License.
* You may obtain a copy of the License at
*
* http://www.apache.org/licenses/LICENSE-2.0
*
* Unless required by applicable law or agreed to in writing, software
* distributed under the License is distributed on an "AS IS" BASIS,
* WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
* See the License for the specific language governing permissions and
* limitations under the License.
*/
package org.opencb.cellbase.lib.builders;
import org.opencb.biodata.formats.feature.gff.Gff2;
import org.opencb.biodata.formats.feature.gff.io.Gff2Reader;
import org.opencb.biodata.formats.io.FileFormatException;
import org.opencb.biodata.models.core.RegulatoryFeature;
import org.opencb.cellbase.core.serializer.CellBaseSerializer;
import org.opencb.cellbase.lib.EtlCommons;
import java.io.IOException;
import java.nio.file.Files;
import java.nio.file.Path;
import java.util.*;
public class RegulatoryFeatureBuilder extends CellBaseBuilder {
private final Path gffFile;
protected Set regulatoryFeatureSet;
public RegulatoryFeatureBuilder(Path regulatoryDirectoryPath, CellBaseSerializer serializer) {
super(serializer);
gffFile = regulatoryDirectoryPath.resolve(EtlCommons.REGULATORY_FEATURES_FILE);
}
@Override
public void parse() throws Exception {
logger.info("Parsing regulatory features...");
if (Files.exists(gffFile)) {
parseGffFile(gffFile);
} else {
logger.warn("No regulatory features GFF file found {}", EtlCommons.REGULATORY_FEATURES_FILE);
logger.warn("Skipping regulatory features GFF file parsing. Regulatory feature data models will not be built.");
}
}
protected void parseGffFile(Path regulatoryFeatureFile) throws IOException, NoSuchMethodException, FileFormatException {
regulatoryFeatureSet = new HashSet<>();
if (regulatoryFeatureFile != null && Files.exists(regulatoryFeatureFile) && !Files.isDirectory(regulatoryFeatureFile)
&& Files.size(regulatoryFeatureFile) > 0) {
Gff2Reader regulatoryFeatureReader = new Gff2Reader(regulatoryFeatureFile);
Gff2 feature;
while ((feature = regulatoryFeatureReader.read()) != null) {
regulatoryFeatureSet.add(feature);
}
regulatoryFeatureReader.close();
}
int i = 0;
// Serialize and save results
for (Gff2 feature : regulatoryFeatureSet) {
// ID=TF_binding_site:ENSR00000243312;
String id = feature.getAttribute().split(";")[0].split(":")[1];
RegulatoryFeature regulatoryFeature = new RegulatoryFeature(id, feature.getSequenceName(), feature.getFeature(),
feature.getStart(), feature.getEnd());
serializer.serialize(regulatoryFeature);
}
serializer.close();
}
}
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